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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M10318 | AC1903 | AC1903 is a specific inhibitor of TRPC5 channel. |
| M10315 | MK6-83 | MK6-83 is an agonist of the transient receptor potential channel ML3 (TRPML3). |
| M9962 | Nonivamide | Nonivamide (also called pelargonic acid vanillylamide or PAVA) can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. |
| M8239 | HC-067047 | HC-067047 is a potent, selective inhibitor of hTRPV4. |
| M7698 | Capsazepine | Capsazepine is a specific vanilloid receptor antagonist; synthetic analog of capsaicin. |
| M7303 | SKF 96365 hydrochloride | SKF 96365 hydrochloride is a tRPC channel blocker; also inhibits store-operated Ca2+ entry. |
| M6983 | ML SA1 | ML SA1 is a activator of TRPML channels. |
| M6705 | EIPA | EIPA is a inhibits TRPP3-mediated currents; also inhibits the Na +/H + exchanger (NHE). |
| M6494 | BCTC | BCTC is a tRPV1 antagonist. BCTC is also a potent and specific inhibitor of transient receptor potential cation channel subfamily M member 8 (TRPM8) in prostate cancer (PCa) DU145 cells. |
| M5349 | (+)-Camphor | Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3. |
| M5154 | Diphenyleneiodonium chloride | Diphenyleneiodonium chloride (DPI) is an irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively. |
| M2960 | Probenecid | Probenecid is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. |
| M2591 | Icilin | Icilin is a synthetic super-agonist of the transient receptor potential M8 (TRPM8) ion channel. |
| M2383 | AMG-517 | AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. |
| M2087 | HC-030031 | HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 μM, respectively). |
| M1846 | SB-705498 | SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1. |
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