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Nonivamide (also called pelargonic acid vanillylamide or PAVA) can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A.
Clin Exp Immunol. 2022 Aug 19;209(2):215-224.
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus
Nonivamide purchased from AbMole
Molecular Weight | 293.4 |
Formula | C17H27NO3 |
CAS Number | 2444-46-4 |
Solubility (25°C) | DMSO 90 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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