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MK6-83

Cat. No. M10315

All AbMole products are for research use only, cannot be used for human consumption.

MK6-83 Structure
Synonym:

MK683

Size Price Availability Quantity
10mg USD 108  USD108 In stock
25mg USD 220  USD220 In stock
50mg USD 372  USD372 In stock
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Quality Control & Documentation
Biological Activity

MK6-83 is an agonist of the transient receptor potential channel ML3 (TRPML3). MK6-83 appears to be significantly more efficacious on fibroblast lysosomes isolated from R403C or V446L expressing cells than on those isolated from TRPML1-/- cells.

Product Citations
Chemical Information
Molecular Weight 336.46
Formula C16H20N2O2S2
CAS Number 1062271-24-2
Solubility (25°C) DMSO 4 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cheng-Chang Chen, et al. Nat Commun. A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV

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Keywords: MK6-83, MK683 supplier, TRP Channel, inhibitors, activators

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