All AbMole products are for research use only, cannot be used for human consumption.
Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. The burning and painful sensations associated with capsaicin result from its chemical interaction with sensory neurons. Capsaicin, as a member of the vanilloid family, binds to a receptor called the vanilloid receptor subtype 1 (VR1). By binding to the VR1 receptor, the capsaicin molecule produces the same sensation that excessive heat or abrasive damage would cause, explaining why the spiciness of capsaicin is described as a burning sensation.
ACS Biomater Sci Eng. 2024 May 13;10(5):2995-3005.
Ca2+ Overload Decreased Cellular Viability in Magnetic Hyperthermia without a Macroscopic Temperature Rise
Capsaicin purchased from AbMole
Signal Transduct Target Ther. 2023 Aug 7;8(1):292.
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice
Capsaicin purchased from AbMole
Cell Signal. 2023 Jun 17.
Neuronal TRPV1-CGRP axis regulates bone defect repair through Hippo signaling pathway
Capsaicin purchased from AbMole
Iran J Basic Med Sci. 2022 May;25(5):635-642.
Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway
Capsaicin purchased from AbMole
| Molecular Weight | 305.41 |
| Formula | C18H27NO3 |
| CAS Number | 404-86-4 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage | 2-8°C, protect from light |
[1] Wytske Fokkens, et al. Capsaicin for Rhinitis
[2] Angela M Chapa-Oliver, et al. Capsaicin: From Plants to a Cancer-Suppressing Agent
[3] Ruth Clark, et al. Anticancer Properties of Capsaicin Against Human Cancer
[5] Surinder Kumar Sharma, et al. Mechanisms and clinical uses of capsaicin
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Products are for research use only. Not for human use. We do not sell to patients.
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