| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8483 | ML099 | ML099 is a Ras-related GTPase activator. |
| M8482 | Nonyloxytryptamine oxalate | Nonyloxytryptamine (5-nonyloxytryptamine) is a potent and selective 5-HT1B receptor agonist. |
| M8481 | KT203 | KT203 is a very potent, selective inhibitor of ABHD6 (IC50 = 0. |
| M8480 | KT182 | KT182 is a very potent, orally bioavailable, selective inhibitor of ABHD6 (a/b-Hydrolase Domain Containing 6). |
| M8479 | Pyr6 | Pyr6 is a selective inhibitor of calcium release from the endoplasmic reticulum via STIM1/Orai1 mediated, store operated calcium entry (SOCE). |
| M8478 | YM-26734 | YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. |
| M8476 | Cuspin-1 | Cuspin-1 (Chemical Upregulator of SMN Protein-1) is an upregulator of the Survival of Motor Neuron protein (SMN), necessary for survival of motor neurons. |
| M8474 | GPBAR-A | GPBAR-A is a very potent agonist of the bile acid receptor GPBA (also known as TGR5). |
| M8473 | RA-9 | RA-9 is a cell permeable and potent inhibitor of the ubiquitin-proteasome system (UPS) that targets deubiquitinating enzymes (DUB) without affecting 20S proteasome catalytic-core activity. |
| M8471 | 2-PMAP | 2-PMAP is a brain penetrant inhibitor of amyloid precursor protein (APP) production. |
| M8469 | Ro 67-4853 | Ro67-4853 is a positive allosteric modulator of metabotropic glutamate 1 (mGlu1) receptors. |
| M8468 | PYZD-4409 | PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. |
| M8467 | OF-1 | OF-1 is a chemical probe for the bromodomains of the BRPF (BRomodomain and PHD Finger containing) family of scaffolding proteins (BRPF1, BRPF2, BRPF3) that assemble histone acetyltransferase (HAT) complexes of the MYST family members MOZ and MORF. |
| M8466 | WWL229 | WWL229 is a highly selective inhibitor of mouse Carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes. |
| M8465 | WWL113 | WWL113 is an inhibitor of mouse Carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes. |
| M8464 | NDMC101 | NDMC101 (HS Cm) is a potent dipeptidyl peptidase-IV (DPPIV) inhibitor in T cells with low cytotoxicity. |
| M8461 | 4BP-TQS | 4BP-TQS is an atypical agonist of a7-nAChR that binds to the receptor in an intrasubunit cavity, and activates the channel via a mechanism that is distinct from conventional agonists. |
| M8460 | Ki11502 | Ki11502 is a potent, ATP-competitive multikinase inhibitor that is selective for PDGF receptor. |
| M8459 | CD40-TRAF6 signaling inhibitor | CD40-TRAF6 signaling inhibitor is a small molecule that binds to TRAF6, blocking interactions with CD40. |
| M8458 | XIB4035 | XIB4035 is a reported agonist of the glial cell-line derived neurotrophic factor (GDNF) receptor GFRα1. |
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