Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M8532 | B32B3 | B32B3 is a potent, selective and cell permeable VprBP inhibitor that suppresses xenograft tumor growth. |
M8530 | BIHC | BIHC is a potent TNF blocker that inhibits the proliferation of various HCC cells. |
M8528 | ML406 | ML406 is an iInhibitor of aminotranferase BioA, the enzyme that catalyzes the second-to-last step of biotin synthesis in Mycobacterium tuberculosis (TB). |
M8527 | Brassinazole | Brassinazole is an inhibitor of the biosynthesis of brassinosteroids, steroid hormones essential for plant growth and development. |
M8526 | MS37452 | MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. |
M8525 | CCT031374 hydrobromide | CCT031374 is an inhibitor of TCF-dependent transcription. |
M8520 | N-Octanoyl dopamine | N-Octanoyl dopamine (NOD) protects cell cultures and tissues from cold storage inflicted damage. |
M8515 | Nifetepimine | Nifetepimine is a dihydropyrimidone calcium channel blocker that down-modulates SERCA3 (sarco/endoplasmic reticulum Ca2+ -ATPase 3) pump, and protects of the CD4+ T cells from tumor-induced apoptosis. |
M8514 | Tesaglitazar | Tesaglitazar is a potent and specific dual PPARα/γ agonist that improves insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. |
M8513 | CLP257 | CLP257 is a selective K+-Cl− cotransporter KCC2 activator that restored impaired Cl− transport in neurons with reduced KCC2 activity. |
M8511 | KT109 | KT109 is a potent and selective inhibitor of Diacylglycerol lipase DAGLβ. |
M8509 | Sephin1 | Sephin1 (selective inhibitor of a holophosphatase) is a guanabez derivative that binds to and inhibits a regulatory subunit of the stress-induced protein phosphatase 1 (PPP1R15A), but not the constitutive PPP1R15B, and lacks ?2-adrenergic activity. |
M8507 | Tonabersat | Tonabersat is a potent inhibitor of neuronal-glial gap junctions in trigeminal ganglion that inhibits cortical spreading depression (CSD) and neurogenic inflammation in animal models of migraine. |
M8505 | CINK4 | CINK4 is a specific inhbitor of CDK4/cyclin D1 complexes (IC50 = 1. |
M8501 | BRD32048 | BRD32048 is a potent inhibitor of ETV1 (ETS variant 1) transcription factor oncoprotein. |
M8499 | VUAA1 | VUAA1 is an agonist of the highly conserved insect odorant receptor co-receptor ion channel Orco. |
M8496 | NSC687852 | NSC687852 is a cell-permeable, potent, reversible and selective inhibitor of 19S regulatory-particle-assoc |
M8495 | Ranirestat | Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. |
M8494 | BMS 204352 | BMS 204352 is a potassium channel modulator. |
M8492 | SQ109 | SQ109 is an anti-tuberculosis compound used in the study of multi-drug resistant tuberculosis (MDR-TB). |
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