| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8406 | DDRI-18 | DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin. |
| M8405 | Febrifugine dihydrochloride | Pyretin is an antimalarial compound and an active component of Changshan Chinese medicine. Recent studies have shown that its mechanism of action is as an inhibitor of proline transfer RNA synthase (ProRS). |
| M8403 | VU0405601 | VU0405601 is a hERG (the human Ether-à-go-go-Related Gene) agonist that increased the IC50 of dofetilide from 38. |
| M8402 | LM11A-31 dihydrochloride | LM11A-31 is a non-peptide ligand of the p75 neurotrophin receptor (p75NTR). |
| M8401 | 2-Methylserotonin maleate | 2-Methylserotonin is a selective full agonist at the 5-HT3 receptor. |
| M8399 | SDZ 220-581 hydrochloride | SDZ 220-581 is a competitive NMDA receptor antagonist that penetrates the blood brain barrier. |
| M8398 | 21H7 | 21H7 is an inhibitor of Wnt/β-catenin signaling that act downstream of the symb-catenin destruction complex to inhibit both Wnt-induced and cancer associated constitutive Wnt signaling via destabilization of β-catenin. |
| M8396 | VU0359595 | VU0359595 is a PLD1 specific inhibitor with an IC50 of 3. |
| M8395 | REDD1 inducer | 6-(1,3-Dioxo-6-(piperidin |
| M8393 | NN414 | NN414 is a potent Kir6. |
| M8389 | SR 27417 | SR 27417 is a long-acting, highly potent, specific competitive platelet-activating factor (PAF) receptor antagonist. |
| M8387 | MI-1 | MI-1 is a Menin-MLL interaction inhibitor. |
| M8386 | IWP-3 | IWP-3 is a Wnt inhibitor that prevents palmitylation of Wnt proteins by Porcupine (Porcn). |
| M8384 | Clonixin | Clonomycin is a non - steroidal anti - inflammatory compound (NSAID) with analgesic effect. |
| M8383 | BIM5078 | BIM5078 is a potent Hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket and modulates the expression of known HNF4a target genes. |
| M8381 | JM6 | JM6 is a precursor compound inhibitor of Kynurenine 3-monooxygenase (KMO) that increases kynurenine acid levels and reduces extracellular glutamate in the brain. |
| M8378 | DCAP | DCAP is a potent broad-spectrum antibiotic that specifically targets the membranes of both Gram-positive and Gram-negative bacteria. |
| M8377 | UCM710 | UCM710 is a dual inhibitor of fatty acid amide hydrolase (FAAH) and α/β hydrolase domain 6 (ABHD6) the enzymes that hydrolyze endocannabinoids. |
| M8376 | BLT-4 | BLT-4 is a blocker of lipid transport-4 (BLT-1). |
| M8375 | S 26948 | S 26948 is a selective PPARγ modulator (SPPARγM). |
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