| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8429 | CLEFMA | CLEFMA is a curcumin analog that elevates ROS levels and induces oxidative stress and apoptosis in lung cancer cell lines. |
| M8427 | MMB-4 | MMB-4 is an oxime that can reactivate cholinesterases that have been inactivated by exposure to organophosphates such as sarin or soman. |
| M8426 | 3-AP-Me | 3-AP-Me is a dimethyl derivative of the ribonucleotide reductase inhibitor 3-AP (SML0568). |
| M8425 | SBI-0087702 | SBI-0087702 promotes the cytoplasmic localization of ATF2 in melanoma cells. |
| M8423 | MKC-733 | MKC-733 is a 5-HT3 specific agonist. |
| M8418 | L-742001 hydrochloride | L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activities as well as viral RNA/complementary RNA promoter binding. |
| M8417 | Geldanamycin-Biotin | Geldanamycin-Biotin is a benzoquinone ansamycin antitumor antibiotic. |
| M8416 | Darglitazone sodium salt | Darglitazone is a highly potent and selective PPAR-γ (peroxisome proliferator-activated receptor-γ) agonist. |
| M8415 | CID44216842 | CID44216842 is a potent and selective non-competitive allosteric inhibitor of Cdc42 GTPase that does not inhabit Rho and Rac. |
| M8413 | DAU-5884 | DAU-5884 is a M3-selective muscarinic receptor antagonist. |
| M8412 | Pivmecillinam | Pivmecillinam is a gram negative antibiotic, and inhibitor of penicillin-binding protein 2 (PBP2). |
| M8411 | Curvularin | S - Curvularin is a macrocyclic lactone with cytotoxic activity. |
| M8410 | Gossypin | Gossypin is an anti-inflammatory pentahydroxyflavone glucoside isolated from Hibiscus vitifolius that is used as an herbal remedy for diabetes, jaundice, and inflammation. |
| M8407 | W-13 | W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells. |
| M8406 | DDRI-18 | DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin. |
| M8405 | Febrifugine dihydrochloride | Pyretin is an antimalarial compound and an active component of Changshan Chinese medicine. Recent studies have shown that its mechanism of action is as an inhibitor of proline transfer RNA synthase (ProRS). |
| M8403 | VU0405601 | VU0405601 is a hERG (the human Ether-à-go-go-Related Gene) agonist that increased the IC50 of dofetilide from 38. |
| M8402 | LM11A-31 dihydrochloride | LM11A-31 is a non-peptide ligand of the p75 neurotrophin receptor (p75NTR). |
| M8401 | 2-Methylserotonin maleate | 2-Methylserotonin is a selective full agonist at the 5-HT3 receptor. |
| M8399 | SDZ 220-581 hydrochloride | SDZ 220-581 is a competitive NMDA receptor antagonist that penetrates the blood brain barrier. |
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