| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8592 | Brassinin | Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. |
| M8588 | iKIX1 | iKIX1 is an antifungal agent that can re-sensitize drug-resistant Candida glabrata to azole antifungals. |
| M8586 | Tazarotenic acid | Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR) that binds to RARα, RARβ, and RARγ. |
| M8585 | Rp-8-Br-cGMPS sodium salt | Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). |
| M8584 | Dapiprazole hydrochloride | Dapiprazole hydrochloride is an an α-adrenergic blocking agent that is used to reverse mydriasis after eye examination. |
| M8583 | Ferutinin | An ERα (estrogen receptor) agonist; phytoestrogen. |
| M8581 | Bis(heptyl)-cognitin dihydrochloride | Bis(heptyl)-cognitin (B7C) is a potent neuroprotective agent and cognitive enhancer. |
| M8580 | Perlapine | Perlapine is a potent and selective agonist of hM3Dq DREADD (Designer Receptors Exclusively Activated by Designer Drugs), which does not activate the native human M3 receptor. |
| M8579 | CMPPE | CMPPE is a GABAB receptor positive allosteric modulator (PAM). |
| M8578 | Undecylprodigiosin hydrochloride | Undecylprodigiosin is a tri-pyrolle antibiotic isolated from Streptomyces coelicolor A3 that exhibits immunosuppressive and apoptotic activities as well as antibacterial, antioxidative and UV protective properties. |
| M8577 | BAY-678 | BAY-678 is an orally available, highly potent and selective inhibitor of human neutrophil elastase (HNE). |
| M8574 | THPN | THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. |
| M8570 | Apratastat | Apratastat (TMI-005) is an orally active, potent and selective dual inhibitor of disintegrin metalloenzyme 17 (ADAM17/ TACE) and matrix metalloprotease (MMP). |
| M8569 | Sitamaquine tosylate | Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. |
| M8568 | DMH2 | DMH2 is a potent antagonist of the BMP receptor activin receptor-like kinase 3 (ALK3, BMPR-IA) that enhance liver regeneration. |
| M8564 | GS39783 | GS39783 is a positive allosteric modulator (PAM) of GABA-B receptors. |
| M8563 | Macelignan | Macelignan is a neuroprotective lingan isolated from nutmeg (Myristica fragrans) that protects dopaminergic neurons from inflammatory degeneration. |
| M8562 | SID 3712249 | SID 3712249 (MiR-544 Inhibitor 1) is an inhibitor of the biogenesis of microRNA-544 (miR-544). |
| M8559 | SR1848 | SR1848 is a cell penetrant and potent inhibitor of orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) that reduces the expression of CyclinD1 and E1, which results in inhibition of cell proliferation. |
| M8557 | CS1 | CS1 is a selective and potent inhibitor of topoisomerase IIα (TopoIIα) that potently inhibits a proliferation of cancer cell lines including MDA-MB-231 and A548 cells, with less toxicity than etoposide. |
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