| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8704 | LRE1 | LRE1 is a selective allosteric inhibitor of soluble adenylyl cyclase (sAC), a ubiquitously expressed, essential component of cAMP-signaling. |
| M8703 | 8-Aminoguanine | 8-amino-guanine, a guanine derivative, is an orally effective potassium-preserving diuretic/sodium compound that increases sodium excretion 17. |
| M8702 | Banoxantrone dihydrochloride | Banoxantrone (AQ4N) is a precursor compound of the hypoxic-activated topoisomerase II inhibitor AQ4(bioreduced AQ4 precursor). |
| M8701 | Inz-1 | Inz-1 is a potent and selective inhibitor of yeast mitochondrial cytochrome bc1 that reverses resistance to triazole antifungals in the pathogenic fungus Candida albicans. |
| M8700 | PCS1055 dihydrochloride | PCS1055 is a potent and selective muscarinic M4 acetylcholine receptor competitive antagonist that exhibits >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor. |
| M8697 | Ibuprofen Arginate | Ibuprofen arginine non-steroidal anti-inflammatory compound (NSAID) the more soluble form of ibuprofen arginine. |
| M8696 | PFM39 | PFM39 is a potent cell-permeable Mirin analog that selectively inhibits MRE11 exo-, but not endo-, nuclease activity. |
| M8695 | BNS | BNS is a cell penetrant, potent and selective inhibitor of prolyl-hydroxylase 2 (PHD2). |
| M8693 | DSHN | DSHN is a potent and selective activator of SHP (small heterodimer partner, NR0B2) that transcriptionally activates SHP mRNA and stabilized the SHP protein by preventing its ubiquitination and degradation. |
| M8688 | ADX71743 | ADX71743 is a brain-penetrant, selective and potent negative allosteric modulator of metabotropic glutamate receptor 7 (mGlu7). |
| M8685 | GSK984 | GSK984 is an inactive control probe for GSK983, which is an inhibitor of dihydroorotate dehydrogenase (DHODH) with antiviral activity. |
| M8684 | GSK983 | GSK983 blocks RNA virus replication with EC50 values of 10–40 nM, and also blocks cell proliferation. |
| M8682 | Imidafenacin hydrochloride | Midanaxine is an effective anti-muscarinic compound with selectivity to muscarinic M3 receptor (Kb = 0). |
| M8681 | ABC44 | ABC44 is a cell-active, potent and selective inhibitor of palmitoyl-protein thioesterase 1 (PPT-1). |
| M8677 | SB-258719 | SB-258719 is a selective and potent 5-HT7 antagonist. |
| M8676 | YU142670 | YU142670 is a selective inhibitor against OCRL1/INPP5F (IC50 = 0. |
| M8675 | APS-2-79 hydrochloride | APS-2-79 is a stabilizer of the Kinase suppressor of Ras (KSR) inactive state, resulting in inhibition of oncogenic Ras signaling, antagonizing the Ras–MAPK pathway. |
| M8671 | UCPH-102 | UCPH-102 is a selective inhibitor of the Excitatory Amino Acid Transporter subtype-1 (EAAT1, GLAST) with an IC50 value of 420 nM for EAAT1 and >300 μM for EAAT2-5. |
| M8670 | 10-Cl-BBQ | 10-Cl-BBQ is an orally bioavailable, non-toxic benzimidazoisoquinoline derivative that acts as an aryl hydrocarbon receptor (AhR) agonist via directly binding to AhR (IC50 = 2. |
| M8669 | L67 | L67 is a potent and specific inhibitor of DNA ligase IIIα (LigIIIα) that preferentially targets mitochondrial LigIIIα resulting in mitochondrial dysfunction. |
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