| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M8765 | Compound C108 | C108 is a small molecule that exhibits cancer-selective cytotoxicity (Viability = 100%/MCF-10A vs. |
| M8763 | Tiotropium bromide monohydrate | Tiotropium Bromide is an anticholinergic broncholidator. |
| M8759 | PS432 | PS432 is an allosteric inhibitor of Protein Kinase C (PKC) that targets regulatory site (PIF-pocket) present in the kinase domain. |
| M8757 | TASIN-1 hydrochloride | TASIN-1 (Truncated APC Selective INhibitor-1) targets EBP- (Emopamil-binding protein; D8-D7 sterol isomerase) dependent cholesterol biosynthesis and selectively induces cellular cholesterol depletion and apoptotic death in human colorectal cancer (CRC) cultures harboring APC truncations under lipid-deficient conditions (0. |
| M8756 | GSK9311 | GSK9311 is a negative control for the SGC epigenetic probe GSK6853. |
| M8754 | Linoleamide | Linoleamide is an endogenous primary fatty acid amide (PFAM) signaling lipid that modulates intracellular Ca2+ homeostasis. |
| M8753 | PKUMDL-WQ-2201 | PKUMDL-WQ-2201 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. |
| M8752 | EF5 | EF5 is a 2-nitroimidazole-based hypoxia marker corresponding to a pentafluorinated derivative of the hypoxic cell-radiation sensitizer etanidazole. |
| M8750 | X-34 | X-34 is a fluorescent, amyloid-specific dye. |
| M8749 | GAT228 | GAT228 is the R-(+)-enantiomer of GAT211, a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling that was found to amplify the therapeutic effect of endocannabinoids without the negative side effects of psychoactivity or tolerance. |
| M8746 | S1QEL1.1 | S1QEL1. |
| M8745 | ITH12575 | ITH12575 is apotent and selective inhibitor of mitochondrial Na+/Ca2+ exchanger mNCX with neuroprotective activity. |
| M8743 | FPMINT | FPMINT is a potent, irreversible and non-competitive inhibitor of equilibrative nucleoside transporters ENT1 and ENT2. |
| M8741 | ADDA 5 hydrochloride | ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) that depletes the bioenergetics reserve capacity in intact glioma cells. |
| M8740 | SN-6 | SN-6 is a selective inhibitor of Na+/Ca++ exchanger (NCX) with some selectivity for the NCX1 isoform. |
| M8739 | TP-472N | TP-472N is a negative control probe for TP-472 (catalog no. |
| M8737 | Equisetin | Equisetin is a tetramic acid analog derived from Fusarium equisti. |
| M8736 | LUF7346 | LUF7346 is a Kv11. |
| M8735 | GAT211 | GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling. |
| M8734 | T1AM | T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. |
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