All AbMole products are for research use only, cannot be used for human consumption.
For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.
INI-43 is a cell penetrant and potent inhibitor of Kpnb1-mediated nuclear import that cancer cell death via a G2–M cell cycle arrest followed by apoptosis. INI-43 inhibits the nuclear localization of Kpnb1 as well as that of its cargo transcription factors, NFY, AP-1, p65, and NFAT. INI-43 exhibit specific cytotoxicity toward cancer cells. INI-43 inhibits tumor growth in cancer xenograft models.
| Molecular Weight | 385.46 |
| Formula | C22H23N7 |
| CAS Number | 881046-01-1 |
| Solubility (25°C) | DMSO: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Products |
|---|
| Adenosine 5'-monophosphate sodium hydrate
Adenosine 5'-monophosphate sodium hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Hydroxylapatite (≈20nm)
Hydroxylapatite (Hydroxyapatite) (≈20nm) is a natural form of calcium phosphate and it can stimulate the expression and secretion of collagen in primary human dermal fibroblasts. Hydroxylapatite nanopowder incorporated into biodegradable polymer composites or deposited onto biocompatible substrates promotes the adhesion and proliferation of osteogenic cells (osteoblasts). Hydroxylapatite has good biocompatibility, bioactivity, and bone conductivity, making it suitable for targeted drug or nucleic acid delivery. |
| Ecromeximab
Ecromeximab (KM 871; KW 2871) is an IgG-κ chimeric antibody targeting ganglioside GD3. |
| 3′-Sialyl-Lewis-a tetrasaccharide
3′-Sialyl-Lewis-a tetrasaccharide (Sialyl Lewis A; SLeA) is a carbohydrate-type antigen that can serve as a tumor marker. 3′-Sialyl-Lewis-a tetrasaccharide is involved in the migration and adhesion of tumor cells. 3′-Sialyl-Lewis-a tetrasaccharide has been used to inhibit the binding of 5B1 antibody to Sialyl-Lewisa -polyvalent biotinylated sLea-PAA. |
| KY-556
KY-556 (N-556) is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
