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Rp-8-Br-cGMPS sodium salt

Cat. No. M8585

All AbMole products are for research use only, cannot be used for human consumption.

Rp-8-Br-cGMPS sodium salt Structure

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Quality Control & Documentation
Biological Activity

Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.

Chemical Information
Molecular Weight 462.15
Formula C10H10BrN5O6PS · Na
CAS Number 208445-06-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cambrian Y Liu, et al. Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents

[2] Jisheng Li, et al. cGMP regulates hydrogen peroxide accumulation in calcium-dependent salt resistance pathway in Arabidopsis thaliana roots

[3] R Andriantsitohaina, et al. Role of endothelial nitric oxide in the response to angiotensin II of small mesenteric arteries of the rat

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