| Cat.No. | Name | Information |
|---|---|---|
| M3326 | Memantine hydrochloride | Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively. |
| M2079 | Chrysin | Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea. |
| M4000 | (±)-Naringenin | (±)-Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines. |
| M11176 | Tebuconazole | Tebuconazole is an agricultural azole fungicide that also inhibits CYP51 for Candida albicans CYP51 (CaCYP51) and truncated human CYP51 (Δ60HsCYP51). IC50 The values are 0.9 and 1.3 μM, respectively. |
| M11164 | SDZ285428 | SDZ285428 is a CYP51 inhibitor. SDZ285428 suppresses Trypanosoma cruzi (TC) CYP51, I/E2 <1 (5 min) and I/E2=9 (1 h). SDZ285428 suppresses Trypanosoma brucei (TB) CYP51, I/E2 <1 (5 min) and I/E2=35 (1 h). |
| M11137 | Dihydromethysticin | Dihydroestherol (Dihydromethysticin) kava lactone, with induced CYP3A23 activity. |
| M10656 | Bergaptol | Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. |
| M10488 | Phthalic acid mono-2-ethylhexyl ester (liquid) | Phthalic acid mono-2-ethylhexyl ester (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP), which inhibits the 17, 20 lyase activity of CYP17. |
| M10057 | α-Naphthoflavone | α-Naphthoflavone is a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis. |
| M9931 | ε-Viniferin | ε-Viniferin is a potent inhibitor for all the CYP family, with Ki values from 0.5-20 μM. |
| M9877 | Rhapontigenin | Rhapontigenin is a selective inactivator of cytochrome P450 1A1 with IC50 of 400 nM. |
| M9684 | (Rac)-Brassinazole | (Rac)-Brassinazole is a brassinosteroid (BR) biosynthesis inhibitor. |
| M9016 | Ezutromid | Ezutromid (BMN-195, SMT C1100) is a first-in-class oral bioavailable utrophin translational modulator with an EC50 value of 0.4 uM. |
| M8186 | Stiripentol | Stiripentol (BCX2600) can be used in the study of the third generation of antiepileptic drugs that enhance gaba energy neurotransmission. It's an inhibitor of cytochrome P450. |
| M7416 | TMS | TMS is a cytochrome P450 1B1 inhibitor. |
| M6451 | Apigenin | Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM. |
| M6389 | 1-Aminobenzotriazole (ABT) | 1-Aminobenzotriazole (ABT) is a cytochrome P450 inhibitor; inhibits 20-HETE synthesis. |
| M6318 | 17-ODYA | 17-ODYA is a lTB ω-hydroxylase inhibitor. |
| M6262 | Fadrozole | Fadrozole is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. |
| M5650 | Fluconazole | Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL. |
| M5557 | Deferasirox | Deferasirox (ICL-670) is an iron chelator that causes iron loss that promotes BclxL downregulation and cell death. Deferasirox (ICL-670) also induced P450 3A4 and inhibited 2C8 and 1A2. |
| M5059 | Furafylline | Furafylline was a potent, non-competitive inhibitor of high affinity phenacetin O-deethylase activity of microsomal fractions of human liver, a reaction catalysed by P450IA2, with an IC50 value of 0.07 microM. |
| M4935 | 3-Cyano-7-ethoxycoumarin | 3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
