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Dihydromethysticin

Cat. No. M11137
Dihydromethysticin  Structure
Size Price Availability Quantity
5mg USD 245  USD245 In stock
10mg USD 400  USD400 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Dihydroestherol (Dihydromethysticin) kava lactone, with induced CYP3A23 activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 276.28
Formula C15H16O5
CAS Number 19902-91-1
Purity >98%
Solubility DMSO ≥ 60 mg/mL
Storage 4°C , protect from light , dry , sealed
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  Catalog
Abmole Inhibitor Catalog




Keywords: Dihydromethysticin supplier, Cytochrome P450 (e.g. CYP17), inhibitors

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