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Stiripentol can be used in the third generation of anti-epileptic studies that enhance gabaergic neurotransmission. Due to its inhibition of several cytochrome P450 enzymes, it has a wide range of pharmacokinetic interactions. Stiripentol also has neuroprotective effects, reducing calcium-mediated neurotoxicity. Stiripentol is also a compound used to study inhibition of neuronal LDH-5 isozyme activity.
| Molecular Weight | 234.29 |
| Formula | C14H18O3 |
| CAS Number | 49763-96-4 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Med Lett Drugs Ther. Stiripentol (Diacomit) for Dravet syndrome
[2] No authors listed. Aust Prescr. Stiripentol for Dravet syndrome
[3] No authors listed. Stiripentol
[4] James E Frampton. Stiripentol: A Review in Dravet Syndrome
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