All AbMole products are for research use only, cannot be used for human consumption.
TMS is a potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. Inhibits cancer cell growth in vitro.
| Molecular Weight | 300.35 |
| Formula | C18H20O4 |
| CAS Number | 24144-92-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 30.04 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Cytochrome P450 (e.g. CYP17) Products |
|---|
| Musk ketone
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. |
| MS-PPOH
MS-PPOH is a potent and selective cytochrome P450 (CYP) epoxygenase inhibitor. |
| (R)-Mephenytoin
(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. |
| (3S,5S)-Atorvastatin
(3S,5S)-Atorvastatin is a inactive enantiomer of Atorvastatin. |
| (3S,5S)-Atorvastatin sodium salt
(3S,5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
