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Tebuconazole

Cat. No. M11176
Tebuconazole Structure
Size Price Availability Quantity
250mg USD 60  USD60 In stock
1g USD 105  USD105 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Tebuconazole is an agricultural azole fungicide that also inhibits CYP51 for Candida albicans CYP51 (CaCYP51) and truncated human CYP51 (Δ60HsCYP51). IC50 The values are 0.9 and 1.3 μM, respectively.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 307.82
Formula C16H22ClN3O
CAS Number 107534-96-3
Purity >99%
Solubility DMSO ≥ 40 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog




Keywords: Tebuconazole supplier, Cytochrome P450 (e.g. CYP17), inhibitors

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