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Cecropin B

Cat. No. M14311
Cecropin B Structure
Size Price Availability Quantity
1mg USD 155  USD155 In stock
5mg USD 460  USD460 In stock
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Quality Control & Documentation
Biological Activity

Cecropin B has high level of antimicrobial activity and is considered as a valuable peptide antibiotic.

Chemical Information
Molecular Weight 3834.67
CAS Number 80451-05-4
Solubility (25°C) Water 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] A Rom Park, et al. Expression of Antimicrobial Peptide (AMP), Cecropin B, in a Fused Form to SUMO Tag With or Without Three-Glycine Linker in Escherichia coli and Evaluation of Bacteriolytic Activity of the Purified AMP

[2] Laura Bedin Denardi, et al. Activity of MSI-78, h-Lf1-11 and cecropin B antimicrobial peptides alone and in combination with voriconazole and amphotericin B against clinical isolates of Fusarium solani

[3] Jiarong Wang, et al. A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties

[4] Jiao Zhang, et al. Label-free liquid crystal biosensor for cecropin B detection

[5] Xiaoqiao Zhou, et al. Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway

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Keywords: Cecropin B supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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