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α-Naphthoflavone

Cat. No. M10057

All AbMole products are for research use only, cannot be used for human consumption.

α-Naphthoflavone Structure
Synonym:

Alpha-Naphthoflavone; αNF

Size Price Availability Quantity
10mg USD 45  USD45 In stock
50mg USD 105  USD105 In stock
100mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

α-Naphthoflavone is a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis.

Chemical Information
Molecular Weight 272.3
Formula C19H12O2
CAS Number 604-59-1
Form Solid
Solubility (25°C) DMSO 20 mg/mL
Storage 2-8°C, protect from light, sealed
References

[1] Po-Lin Liao, et al. Exp Dermatol. Anti-ageing effects of alpha-naphthoflavone on normal and UVB-irradiated human skin fibroblasts

[2] Iain A Murray, et al. Mol Pharmacol. Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone

[3] D R Campbell, et al. J Steroid Biochem Mol Biol. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes

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Keywords: α-Naphthoflavone, Alpha-Naphthoflavone; αNF supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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