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ε-​Viniferin

Cat. No. M9931
ε-​Viniferin Structure
Synonym:

epsilon-Viniferin

Size Price Availability
5mg USD 450  USD450 4-7 Days
10mg USD 750  USD750 4-7 Days
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Quality Control & Documentation
Biological Activity

ε-Viniferin is a potent inhibitor for all the CYP family, with Ki values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant capacity.

Chemical Information
Molecular Weight 454.47
Formula C28H22O6
CAS Number 62218-08-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Xavier Vitrac, et al. J Agric Food Chem. Determination of stilbenes (delta-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, epsilon-viniferin) in Brazilian wines

[2] Bertrand Piver, et al. Life Sci. Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages

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Keywords: ε-​Viniferin, epsilon-Viniferin supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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