About 31 results found for searched term "D-Pro-Pro-Glu" (0.105 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M44650 | (2R)-3-Hydroxy-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]propyl beta-D-glucopyranoside | Others |
| (2R)-3-Hydroxy-2-[4-(3-hydroxypropyl)-2- methoxyphenoxy]propyl beta-D-glucopyranoside | ||
| M44651 | (2S)-3-Hydroxy-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]propyl beta-D-glucopyranoside | Others |
| (2S)-3-Hydroxy-2-[4-(3-hydroxypropyl)-2- methoxyphenoxy]propyl beta-D-glucopyranoside | ||
| M50770 | D-Pro-Pro-Glu | Others |
| D-Pro-Pro-Glu is a tripeptide catalyst. | ||
| M4182 | Isochlorogenic-acid-B | Anti-infection |
| 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B | ||
| 3, 4-dicaffeoylquinic acid is naturally isolated and has antioxidant, DNA protective, neuroprotective and liver protective properties. 3, 4-dicaffeoylquinic acid has apoptosis-mediated cytotoxicity and α-glucosidase inhibition. 3, 4-dicaffeoylquinic acid has a unique antiviral mechanism, that is, by increasing TRAIL, the virus clearance rate can be improved. | ||
| M4306 | Ganoderic-acid-D | Sirtuin |
| Ganoderic acid D is a highly oxidized tetracyclic triterpenoid that is the main active ingredient in Ganoderma lucidum. Ganoderic acid D upregulates protein expression for SIRT3 and induces deacetylated cyclophilic protein D (CypD) through SIRT3. Ganoderic acid D inhibits energy reprogramming in colon cancer cells, including glucose uptake, lactate production, pyruvate, and acetyl-Coenzyme production in colon cancer cells. | ||
| M4352 | (-)-Licarin-B | PPAR |
| Licarin B, derived from the seed of Myristica Fragrans, is an inhibitor of NO production that improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway. | ||
| M6276 | Thiazolidine | PPAR |
| Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor γ agonists that improve insulin-mediated glucose uptake and possess beneficial vasculoprotective actions. | ||
| M10526 | L-Alanine | Metabolite/Endogenous Metabolite |
| L-Alanine (also called 2-aminopropanoic acid, α-aminopropanoic acid) is an amino acid that helps the body convert the simple glucose into energy and eliminate excess toxins from the liver. | ||
| M10999 | Luteolin 5-O-glucoside | NO Synthase |
| Luteolin 5-O-glucoside from Cirsium maackii has anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS production. Luteolin 5-O-glucoside acts on macrophages and also inhibits iNOS and COX-2 expression. | ||
| M11113 | (R,R)-Secoisolariciresinol diglucoside | Others |
| (R,R)-SDG | ||
| (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is a minor subtype of Secoisolariciresinol diglucoside present in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) has antioxidant properties, free radical scavenging activity, and DNA-radiation protection. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by inhibiting peroxidase and chloride cycles in inflammatory cells. | ||
| M14438 | Castanospermine | Others |
| Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). | ||
| M18349 | Theaflavin-3’-gallate | Others |
| Theaflavin-3’-gallate is the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. | ||
| M19966 | PSMA-11 | PSMA |
| PSMA11 | ||
| Psma-11 is a positron emission tomography (PET) tracer. Psma-11 detects recurrence and metastasis of prostate cancer by binding to the extracellular region of prostate specific membrane antigen (PSMA). Sequence: Glu - NH - CO - NH - Lys (Ahx) - HBED - CC | ||
| M20599 | PI-1840 | Proteasome |
| PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 nM with little effects on the other two major proteasome proteolytic activities, trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L). | ||
| M21299 | D-Glucosemonohydrate | Cell Culture |
| D-(+)-glucose monohydrate is a common natural sugar involved in processes such as glycosylation, energy production, and the formation of glycans, which are structural components of cells. d-(+)-glucose monohydrate can also cause glycation, which is a harmful process in cells. It is used as a supplement for many cellular processes and cell culture. | ||
| M21411 | Recombinant Rat S100A8 (E.coli , C-6His) | Cytokines and Growth Factors |
| Protein S100-A8; Calgranulin-A | ||
| Recombinant rat S100 calcium-binding protein A8 is produced by the E. coli expression system and the target gene encoding Met1-Glu89 has a 6His tag at the C-terminus. Protein ID:P50115. | ||
| M21698 | Lectin from Phytolacca americana (pokeweed) | Others |
| Pokeweed mitogen; PWM | ||
| Pokeweed mitogen (PWM) is extracted from pokeweed roots. This protein has hemagglutinating, leukoagglutinating, and mitogenic properties. PWM is not blood group specific, but has affinity for N-acetyl-β-D-glucosamine oligomers. | ||
| M22506 | Recombinant Human ANGPTL4 (HEK293, N-6His) | Cytokines and Growth Factors |
| Angiopoietin Like Protein 4; Angiopoietin-related protein 4 | ||
| Recombinant Human Angiopoietin Like Protein 4 is produced by Mammalian expression system and the target gene encoding Pro166-Ser406 is expressed with a 6His tag at the N-terminus. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). | ||
| M25422 | Glypromate acetate | NMDA |
| Gly-Pro-Glu | ||
| Glypromate acetate is a neuroactive peptide with a potent action on acetylcholine release. Glypromate (Gly-Pro-Glu) is a weak NMDA receptor agonist binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. | ||
| M28249 | AMG-1694 | Glucokinase (GK) |
| AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity and promotes GK translocation. AMG-1694 normalizes blood glucose levels in several rodent models of diabetes and lowes blood glucose restricted to diabetic and not normoglycaemic animals. | ||
| M28622 | RO6889678 | Anti-infection |
| RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation. | ||
| M28758 | YIL781 hydrochloride | Ghrelin Receptor/GHSR |
| YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL-781 hydrochloride inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively. | ||
| M28765 | SLMP53-1 | p53 |
| SLMP53-1 is a wild-type and mutant p53 reactivator with promising antitumor activity. SLMP53-1 mediates the reprograming of glucose metabolism in cancer cells. SLMP53-1 depletes angiogenesis, decreasing endothelial cell tube formation and vascular endothelial growth factor (VEGF) expression levels. | ||
| M30594 | Beclometasone dipropionate monohydrate | GCR |
| Beclometasone dipropionate monohydrate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma . | ||
| M30783 | YIL781 | Ghrelin Receptor/GHSR |
| YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL-781 hydrochloride inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively. | ||
| M31283 | Glucose oxidase | Metabolite/Endogenous Metabolite |
| GOD; EC 1.1.2.3.4; beta-D-glucose:oxygen 1-oxidoreductase | ||
| Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells. | ||
| M38996 | Kazinol B | NO Synthase |
| Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research. | ||
| M40644 | PreScission Protease | Enzymes & Coenzymes |
| HRV 3C Protease; HRV3C Protease | ||
| PreScission Protease is a recombinantly expressed 3C protease of human rhinovirus type 14 with a GST tag in Escherichia coli that specifically recognizes the octapeptide sequence Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro or the core pentapeptide sequence Leu-Phe-Gln-Gly-Pro at low temperature (4°C) and cleaves between Gln and Gly amino acid residues. Pro and enzymatically cleaves between Gln and Gly amino acid residues, commonly used to remove Glutathione S-transferase (GST), His, or other tags from fusion proteins. | ||
| M41832 | LSN3160440 | GLP Receptor |
| LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R. | ||
| M43784 | Pterosin A | Others |
| Pterosin A is a natural product isolated from Pteridium aquilinum with oral activity that promotes glucose uptake, increases serum insulin, and improves hyperglycemia and glucose intolerance in diabetic mice. It can be used in studies related to diabetes. | ||
| M45324 | α-Amylase | Amylases |
| α-Amylase is a hydrolase that catalyzes the hydrolysis of the α-1,4-glycosidic bond in starch to produce products such as glucose and maltose. | ||
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