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D-Glucosemonohydrate

Cat. No. M21299
D-Glucosemonohydrate Structure
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500g USD 65  USD65 In stock
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Quality Control & Documentation
Biological Activity

D-(+)-glucose monohydrate is a common natural sugar involved in processes such as glycosylation, energy production, and the formation of glycans, which are structural components of cells. d-(+)-glucose monohydrate can also cause glycation, which is a harmful process in cells. It is used as a supplement for many cellular processes and cell culture.

Chemical Information
Molecular Weight 198.17
Formula C6H14O7
CAS Number 14431-43-7
Solubility (25°C) Soluble in Ethanol
Storage RT
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Gregory C Bogdanis, et al. Nutrients. Effects of Oral Creatine Supplementation on Power Output during Repeated Treadmill Sprinting

[2] Xing-Liang Yang, et al. J Neuroinflammation. TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI)

[3] No authors listed. Saxagliptin

[4] Michelle A Ponschke, et al. Carbohydr Res. Kinetic studies on the loss of water from α-D-glucose monohydrate

[5] Johann van der Merwe, et al. Clin J Sport Med. Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players

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