L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.
Int J Chron Obstruct Pulmon Dis. 2021 Jun 4;16:1661-1675.
Anticancer Res. 2021 May;41(5):2257-2275.
Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Dгυg Screening
L-Glutamine purchased from AbMole
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Solubility||Water 36 mg/mL|
The Influence of Oral L-Glutamine Supplementation on Muscle Strength Recovery and Soreness Following Unilateral Knee Extension Eccentric Exercise.
Legault Z, et al. Int J Sport Nutr Exerc Metab. 2015 Oct;25(5):417-26. PMID: 25811544.
|Related GluR Products|
Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation.
L-Methionine sulfoximine is a potent inhibitor of glutamine sythetase (GS) activity, used as a selection agent for plasmid integration in Chinese hamster ovary (CHO) and other mammalian cell lines.
Decoglurant (also known as RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors.
Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
CX546 is a selective positive AMPA glutamate receptor modulator.
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