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L-Glutamine

Cat. No. M5740
L-Glutamine Structure
Synonym:

L-Glutamic acid 5-amide

Size Price Availability Quantity
100mg USD 35  USD35 In stock
500mg USD 55  USD55 In stock
5g USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.

Product Citations
Chemical Information
Molecular Weight 146.14
Formula C5H10N2O3
CAS Number 56-85-9
Solubility (25°C) Water 36 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Legault Z, et al. Int J Sport Nutr Exerc Metab. The Influence of Oral L-Glutamine Supplementation on Muscle Strength Recovery and Soreness Following Unilateral Knee Extension Eccentric Exercise.

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