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D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response
J Tissue Viability. 2022 Aug 20;S0965-206X(22)00093-6.
Astragaloside IV attenuates high glucose-induced human keratinocytes injury via TGF-β/Smad signaling pathway
D-Glucose purchased from AbMole
J Sport Health Sci . 2022 Jul;11(4):466-478.
Lymphangiogenesis contributes to exercise-induced physiological cardiac growth
D-Glucose purchased from AbMole
Aging Cell. 2021 Jan;20(1):e13282.
SPATA4 improves aging-induced metabolic dysfunction through promotion of preadipocyte differentiation and adipose tissue expansion
D-Glucose purchased from AbMole
Environ Health Perspect. 2020 Jun;128(6):67008.
Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation
D-Glucose purchased from AbMole
| Molecular Weight | 180.16 |
| Formula | C6H12O6 |
| CAS Number | 50-99-7 |
| Solubility (25°C) | Water 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Endogenous Metabolite Products |
|---|
| 22(R)-Hydroxycholesterol
22(R)-Hydroxycholesterol is an intermediate of the pregnenolone synthesis pathway from cholesterol. It has neuroprotective properties and protects the neurons against β-amyloid-induced cell death. |
| Deltamethrin
Deltamethrin produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis. |
| Adenosine 5′-triphosphate magnesium salt
Adenosine 5′-triphosphate magnesium salt is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. |
| Phosphocreatine
Phosphocreatine, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction |
| 2'3'-cGAMP
2'3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm. |
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