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RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation.
| Molecular Weight | 494.92 |
| Formula | C21H20ClFN4O5S |
| CAS Number | 1578153-27-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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