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Abmole Inhibitor Catalog 2017

NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells


Cat.No.  Name Information
M10653 Dehydroevodiamine Dehydroevodiamine has an antiarrhythmic effect in guinea-pig ventricular myocytes. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.
M10545 SN50 SN50 is a cell permeable inhibitor of NF-κB translocation.
M9949 NIK SMI1 NIK SMI1 is a highly selective and potent NF-κB-inducing kinase (NIK) inhibitor.
M9825 Helenalin Helenalin is an anti-inflammatory sesquiterpene lactone, it selectively inhibits transcription factor NF-κB by directly targeting p65.
M9645 Licochalcone D Licochalcone D is a potent inhibitor of NF-kappaB (NF-κB) p65 with antioxidant, anti-inflammatory, anti-cancer properties.
M9456 Berbamine dihydrochloride Berbamine dihydrochloride is a novel inhibitor of NF-κB, inhibits growth and induces apoptosis in human myeloma cells.
M8600 Urolithin B Urolithin B is a natural product with antiproliferative and antioxidant activity.
M6180 AZD3264 AZD3264 is a novel IKK2 inhibitor.
M6179 Diethylmaleate Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
M5580 Dimethyl Fumarate Dimethyl fumarate(DMF) is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator; induces upregulation of antioxidant gene expression.
M5371 5-Aminosalicylic acid 5-Aminosalicylic acid is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.
M5232 GSK583 GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM.
M4940 SC75741 SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
M4550 Maslinic-acid Maslinic-acid (MA) is a Natural Triterpene, exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating.
M4067 Ginsenoside-Rg2 Ginsenoside-Rg2 is one of the major active components of ginseng, acts as a NF-κB inhibitor.
M4005 Pyrrolidinedithiocarbamate ammonium (PDTC) Pyrrolidinedithiocarbamate ammonium (PDTC) is a selective nuclear factor-κB (NF-κB) inhibitor.
M3963 Bruceine A Bruceine A, a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) Merr., was evaluated for its antibabesial activity in vitro and in vivo.
M3930 Parthenolide Parthenolide (PTL) is a sesquiterpene lactone isolated from feverfew and exhibits potent antitumor activity against various cancers.
M3161 Betulinic acid Betulinic acid is a pentacyclic triterpene which selectively induces apoptosis in tumor cells. It acts as a new activator of NF-kB.
M3017 Sodium 4-Aminosalicylate Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
M2844 Methylthiouracil Methylthiouracil is an antithyroid preparation, Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
M2786 JSH-23 JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
M2484 Caffeic Acid Phenethyl Ester Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
M2298 QNZ QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM.
M2197 Sulfasalazine Sulfasalazine is an inhibitor of NF-κB activation and a procompound of the anti-inflammatory agent 5-aminosalicylic acid.

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