| Cat.No. | Name | Information |
|---|---|---|
| M4005 | PDTC | Pyrrolidinedithiocarbamate ammonium (PDTC) is a selective and blood-brain barrier (BBB) permeable nuclear factor-κB (NF-κB) inhibitor. |
| M4940 | SC75741 | SC75741 is a broad and potent INHIBITOR of NF-κB with an IC50 of 200 nM against P65. SC75741 blocks replication of influenza viruses. SC75741 leads to decreased expression of cytokines, chemokines, and pro-apoptotic factors by impairing DNA binding of NF-κB subunit P65. Inhibit caspase activation and block caspase-mediated nuclear output of viralribonucleoproteins. |
| M3985 | Triptolide | Triptolide is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities. |
| M9331 | Royal Jelly acid | Royal Jelly acid (10-hydroxy-2-decenoic acid) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M2298 | QNZ | QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. |
| M7490 | Withaferin A | Withaferin A is a steroidal ester isolated from nightfruit, which can inhibit the activity of NF-kB, target vimentin, and has anti-inflammatory, anti-tumor and other effects. |
| M2786 | JSH-23 | Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα. |
| M6179 | Diethylmaleate | Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. |
| M5371 | 5-Aminosalicylic acid | 5-aminosalicylic acid (Mesalamine) is a specific PPARγ agonist that also inhibits P21-activated kinase 1 (PAK1) and NF-κB. |
| M7588 | N-acetylcysteine amide | N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that crosses cell membranes and the blood-brain barrier, has anti-inflammatory activity, and is able to modulate NF-κB activation, HIF-1α and ROS. |
| M2501 | Cepharanthine | Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
| M2484 | Caffeic Acid Phenethyl Ester | Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| M56832 | DCZ5418 | DCZ5418 is an inhibitor of TRIP13. |
| M56831 | Ro 106-9920 | Ro 106-9920 is a potent inhibitor of NF-kappaB. |
| M56288 | MRS2693 trisodium | MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM. |
| M54521 | Narlumosbart | Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB). |
| M54279 | Ac2-26 | Ac2-26, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. |
| M52815 | Mitogen-activated protein kinase 1 | Mitogen-activated protein kinase 1 (MAPK1) can activate the downstream p38/NF-κB pathway. |
| M52370 | IKKγ NBD Inhibitory Peptide | IKKγ NBD Inhibitory Peptide is a highly specific inhibitor NF-κB inhibitor. |
| M52369 | Tripeptide-41 | Tripeptide-41(CG-Lipoxyn)isa bioactive peptide withreduce fat accumulationeffect and has been reported used as a cosmetic ingredient. |
| M52368 | CTP-NBD | CTP-NBD is a cell permeable specific NFκB peptide inhibitor. |
| M44758 | 9,10-Dimethoxycanthin-6-one | 9,10-Dimethoxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 19.5 μM. |
| M44756 | 7-Hydroxy-4'-methoxyflavone | Pratol is a potent inhibitor of NF-κB. |
| M44692 | 2,4,6-Trihydroxybenzaldehyde | 2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity. |
| M42751 | NF-κB-IN-11 | NF-κB-IN-11 is a NF-κB inhibitor. |
| M42750 | 7-O-Methylaloesinol | 7-O-Methylaloesinol is a chromone derivative. |
| M42749 | 9-Hydroxycanthin-6-one | 9-Hydroxycanthin-6-one is an alkaloid compound. |
| M42748 | NF-κB-IN-8 | NF-κB-IN-8 competitively antagonizes LPS binding to MD-2. |
| M42747 | Eudebeiolide B | Eudebeiolide B is a compound that can be isolated from Salvia plebeia R. |
| M42746 | Phenyl β-D-glucopyranoside | Phenyl β-D-glucopyranoside has anti-cancer and anti-inflammatory activities. |
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