| Cat.No. | Name | Information |
|---|---|---|
| M4005 | Pyrrolidinedithiocarbamate ammonium (PDTC) | Pyrrolidinedithiocarbamate ammonium (PDTC) is a selective nuclear factor-κB (NF-κB) inhibitor. |
| M5580 | Dimethyl Fumarate | Dimethyl Fumarate (DMF) is an orally active Monomethyl fumarate (MMF) precursor compound that is also an Nrf2 pathway activator and inhibits NF-κB. In addition, Dimethyl Fumarate also inhibits GAPDH and can be used in studies related to multiple sclerosis (MS) and psoriasis. |
| M4940 | SC75741 | SC75741 is a broad and potent INHIBITOR of NF-κB with an IC50 of 200 nM against P65. SC75741 blocks replication of influenza viruses. SC75741 leads to decreased expression of cytokines, chemokines, and pro-apoptotic factors by impairing DNA binding of NF-κB subunit P65. Inhibit caspase activation and block caspase-mediated nuclear output of viralribonucleoproteins. |
| M3985 | Triptolide | Triptolide is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities. |
| M2298 | QNZ | QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. |
| M7490 | Withaferin A | Withaferin A is a steroidal ester isolated from nightfruit, which can inhibit the activity of NF-kB, target vimentin, and has anti-inflammatory, anti-tumor and other effects. |
| M2786 | JSH-23 | Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα. |
| M6179 | Diethylmaleate | Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. |
| M52368 | CTP-NBD | CTP-NBD is a cell permeable specific NFκB peptide inhibitor. |
| M44758 | 9,10-Dimethoxycanthin-6-one | 9,10-Dimethoxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 19.5 μM. |
| M44756 | 7-Hydroxy-4'-methoxyflavone | Pratol is a potent inhibitor of NF-κB. |
| M44692 | 2,4,6-Trihydroxybenzaldehyde | 2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity. |
| M42751 | NF-κB-IN-11 | NF-κB-IN-11 is a NF-κB inhibitor. |
| M42750 | 7-O-Methylaloesinol | 7-O-Methylaloesinol is a chromone derivative. |
| M42749 | 9-Hydroxycanthin-6-one | 9-Hydroxycanthin-6-one is an alkaloid compound. |
| M42748 | NF-κB-IN-8 | NF-κB-IN-8 competitively antagonizes LPS binding to MD-2. |
| M42747 | Eudebeiolide B | Eudebeiolide B is a compound that can be isolated from Salvia plebeia R. |
| M42746 | Phenyl β-D-glucopyranoside | Phenyl β-D-glucopyranoside has anti-cancer and anti-inflammatory activities. |
| M42745 | Demethyleneberberine chloride | Demethyleneberberine chloride is a natural mitochondria-targeted antioxidant. |
| M42744 | EN450 | EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. |
| M42743 | ALPK1-IN-3 | ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. |
| M42742 | Torilin | Torilin is a sesquiterpene with antimicrobial, anticancer, and anti-inflammatory properties. |
| M42741 | NF-κB-IN-9 | NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm). |
| M42740 | Vitisin A | Vitisin A has antioxidative, anticancer, antiapoptotic, neuroprotective and anti-inflammatory effects. |
| M42739 | Sanggenon A | Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. |
| M42738 | NF-κB-IN-10 | NF-κB-IN-10 is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. |
| M42531 | Inotilone | Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. |
| M39222 | Echinulin | Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent. |
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