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Cepharanthine

Cat. No. M2501

All AbMole products are for research use only, cannot be used for human consumption.

Cepharanthine Structure
Synonym:

NSC-623442

Size Price Availability Quantity
50mg USD 50  USD50 In stock
100mg USD 75  USD75 In stock
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Quality Control & Documentation
Biological Activity

Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.

Chemical Information
Molecular Weight 606.71
Formula C37H38N2O6
CAS Number 481-49-2
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xuan Zhang, et al. Cepharanthine, a novel selective ANO1 inhibitor with potential for lung adenocarcinoma therapy

[2] Hirofumi Ohashi, et al. Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment

[3] Moshe Rogosnitzky, et al. Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

[4] Yao Wang, et al. Cepharanthine hydrochloride induces mitophagy targeting GPR30 in hepatocellular carcinoma (HCC)

[5] Christian Bailly. Cepharanthine: An update of its mode of action, pharmacological properties and medical applications

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Keywords: Cepharanthine, NSC-623442 supplier, NF-κB, inhibitors, activators

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