| Cat.No. | Name | Information |
|---|---|---|
| M2129 | Temozolomide | Temozolomide (TMZ) is an oral DNA methylating, chemotherapeutic agent. |
| M2223 | Cisplatin | Cisplatin is an inorganic platinum complex that inhibits DNA synthesis by forming DNA crosslinking agents, inactivates GPXs, reduces cell GSH and induces iron death in HCT116 and A549 cells. |
| M2289 | 5-Fluorouracil | 5-Fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. |
| M2288 | Carboplatin | Carboplatin (NSC 241240) is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism. |
| M2292 | Cytarabine | Cytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM. |
| M1716 | Gemcitabine Hydrochloride | Gemcitabine (Gemzar, LY188011) inhibits DNA synthesis with an IC50 of 0.06 µM. |
| M5680 | Gemcitabine | Gemcitabine (LY-188011; NSC 613327) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis. |
| M5277 | B02 | B02 is a small-molecule inhibitor of human RAD51 with an IC50 of 27.4 μM, but does not inhibit its E. coli homologue RecA (IC50 > 250 μM). |
| M7515 | Brivudine | Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication. |
| M9650 | Triazavirin | Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent, works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. |
| M49841 | Werner syndrome RecQ helicase-IN-4 | Werner syndrome RecQ helicase-IN-4 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity. |
| M49840 | Werner syndrome RecQ helicase-IN-2 | Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research. |
| M44721 | 3-Hydroxy-2-methylpyridine | 3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine. |
| M43833 | DMT-dT-CE | DMT-dT-CE is typically used in the synthesis of DNA. |
| M43832 | DMT-dC(Ac)-CE | DMT-dC(Ac)-CE is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis. |
| M43831 | DMT-dC(Bz)-CE | DMT-dC(Bz)-CE is typically used in the synthesis of DNA. |
| M43830 | DMT-dG(dmf)-CE | DMT-dG(dmf)-CE is a phosphinamide monomer that can be used in the preparation of oligonucleotides. |
| M43829 | DMT-dG(iBu)-CE | DMT-dG(iBu)-CE is typically used in the synthesis of DNA. |
| M43828 | DMT-dA(Bz)-CE | DMT-dA(Bz)-CE is typically used in the synthesis of DNA. |
| M42913 | WRN inhibitor 4 | WRN inhibitor 4, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. |
| M41479 | DIZ-3 | DIZ-3 is a selective multimeric G4 ligand based on a G4-ligand-dimerizing strategy. |
| M41478 | MTR-106 | MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. |
| M41473 | qsl-304 | qsl-304 is a DNA gyrase B inhibitor. |
| M41472 | DNA Gyrase-IN-7 | DNA Gyrase-IN-7 is a novel Microbial DNA-Gyrase inhibitor. |
| M41471 | RNase L-IN-1 | RNase L-IN-1 is an inhibitor of RNase L, or Ribonuclease L. |
| M41470 | Votoplam | Votoplam is a gene splicing modulator, used to inhibit Huntington's disease. |
| M41469 | DNA Gyrase-IN-8 | DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. |
| M41468 | RdRP-IN-6 | RdRP-IN-6 inhibits RNA dependent-RNA polymerase (RdRp) with an IC90 value of 14.1 μM. |
| M41467 | Ara-ATP | Ara-ATP, a structural analog of ATP, inhibits poly(A) polymerase activity by competing with ATP. |
| M41466 | 3-Cyanovinylcarbazole phosphoramidite | 3-Cyanovinylcarbazole phosphoramidite is an antiviral agent that inhibits the synthesis of viral DNA. |
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