| Cat.No. | Name | Information |
|---|---|---|
| M4879 | Cycloheximide | Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, with IC50 of 532.5 nM. |
| M2129 | Temozolomide | Temozolomide (TMZ) is an oral DNA methylating, chemotherapeutic agent. |
| M2223 | Cisplatin | Cisplatin is an inorganic platinum complex that inhibits DNA synthesis by forming DNA crosslinking agents, inactivates GPXs, reduces cell GSH and induces iron death in HCT116 and A549 cells. |
| M2289 | 5-fluorouracil | 5-fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. |
| M2288 | Carboplatin | Carboplatin (NSC 241240) is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism. |
| M2292 | Cytarabine | Cytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM. |
| M1716 | Gemcitabine Hydrochloride | Gemcitabine (Gemzar, LY188011) inhibits DNA synthesis with an IC50 of 0.06 µM. |
| M5680 | Gemcitabine | Gemcitabine(LY-188011; NSC 613327) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. |
| M5277 | B02 | B02 is a small-molecule inhibitor of human RAD51 with an IC50 of 27.4 μM, but does not inhibit its E. coli homologue RecA (IC50 > 250 μM). |
| M7515 | Brivudine | Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication. |
| M43830 | DMT-dG(dmf)-CE | DMT-dG(dmf)-CE is a phosphinamide monomer that can be used in the preparation of oligonucleotides. |
| M43829 | DMT-dG(iBu)-CE | DMT-dG(iBu)-CE is typically used in the synthesis of DNA. |
| M43828 | DMT-dA(Bz)-CE | DMT-dA(Bz)-CE is typically used in the synthesis of DNA. |
| M43827 | Pseudo-UTP | Pseudo-UTP is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties. |
| M42913 | WRN inhibitor 4 | WRN inhibitor 4, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. |
| M41479 | DIZ-3 | DIZ-3 is a selective multimeric G4 ligand based on a G4-ligand-dimerizing strategy. |
| M41478 | MTR-106 | MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. |
| M41473 | qsl-304 | qsl-304 is a DNA gyrase B inhibitor. |
| M41472 | DNA Gyrase-IN-7 | DNA Gyrase-IN-7 is a novel Microbial DNA-Gyrase inhibitor. |
| M41471 | RNase L-IN-1 | RNase L-IN-1 is an inhibitor of RNase L, or Ribonuclease L. |
| M41470 | Votoplam | Votoplam is a gene splicing modulator, used to inhibit Huntington's disease. |
| M41469 | DNA Gyrase-IN-8 | DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. |
| M41468 | RdRP-IN-6 | RdRP-IN-6 inhibits RNA dependent-RNA polymerase (RdRp) with an IC90 value of 14.1 μM. |
| M41467 | Ara-ATP | Ara-ATP, a structural analog of ATP, inhibits poly(A) polymerase activity by competing with ATP. |
| M41466 | 3-Cyanovinylcarbazole phosphoramidite | 3-Cyanovinylcarbazole phosphoramidite is an antiviral agent that inhibits the synthesis of viral DNA. |
| M41465 | WRN inhibitor 2 | WRN inhibitor 2 is a WRN (Werner Syndrome ATP dependent helicase enzyme) inhibitor, with pIC50 ≥ 7.0. |
| M41464 | EDTA dipotassium dihydrate | EDTA (Ethylenediaminetetraacetic acid) dipotassium dihydrate is anticoagulants, chelating heavy metal and relieve toxicity. |
| M41463 | H3B-968 | H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM), which acts function as helicase, ATPase, and exonuclease. |
| M41462 | WRN inhibitor 1 | WRN inhibitor 1 is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor that inhibits WRN helicase domain activity. |
| M41461 | SRE-II | SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. |
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