| Cat.No. | Name | Information |
|---|---|---|
| M9075 | (R)-(+)-Etomoxir sodium salt | (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M8392 | Tirapazamine | Tirapazamine (TPZ，SR-4233, WIN 59075) is the first hypoxia-activated prodrug. Tirapazamine kills hypoxic cells by inducing chromosome aberrations and DNA double-strand breaks. Tirapazamine induced cell cycle arrest and apoptosis, and down-regulated HIF-1α, CA-IX and VEGF expression. |
| M8258 | KYP-2047 | KYP-2047 is a potent and BBB-penetrating prolyl-oligopeptidase (POP) inhibitor, with an Ki value of 0.023 nM. KYP-2047 reduces glioblastoma proliferation through angiogenesis and apoptosis modulation. |
| M7755 | Dehydroleucodine | Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. |
| M7622 | BI-6C9 | BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from mitochondrial apoptosis inducing factor (AIF) release and caspase-independent cell death in neurons. |
| M7576 | Importazole | Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β. |
| M7341 | Swainsonine | Swainsonine is a inhibitor of α-mannosidase II. |
| M7145 | Pladienolide B | Pladienolide B is a potent pre-mRNA splicing inhibitor, exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B induces apoptosis. |
| M6673 | DIM-C-pPhOH | DIM-C-pPhOH is a nur77 antagonist. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively. |
| M6567 | CCCP | CCCP is a oxidative phosphorylation uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation. |
| M6553 | C16 | C16 is a pKR inhibitor. |
| M6313 | PTC-028 | PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification. |
| M6290 | Puromycin aminonucleoside | Puromycin aminonucleoside (PAN), which is an analogue of puromycin antibiotic, has been largely adopted to experimentally induce MCD in rodents (with a single high dose) or FSGS (by repeated doses for over a longer period). |
| M5761 | Mangafodipir trisodium | Mangafodipir is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. |
| M5689 | Hesperidin | Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols. |
| M5636 | Etretinate | Etretinate is an orally available aromatic retinoid that has been shown to be effective in studies of cow skin and other skin syndromes. It can activate retinoid receptor, induce cell differentiation, inhibit cell proliferation and inhibit tissue infiltration. |
| M5632 | Etidronate | Etidronate is a class of non-aminobisphosphate that inhibits human protein tyrosine phosphatase activity and is used in the study of Paget's disease and in the prevention of ectopic ossification. |
| M5623 | Escin | Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut). |
| M5568 | Diatrizoic acid | Diatrizoic Acid is an organic, iodinated radiocontrast agent used in diagnostic radiography. |
| M5298 | NSC-144303 | Ubiquitin Isopeptidase Inhibitor I, G5 (NSC-144303) is a broad-spectrum cell-permeable deubiquitinating enzyme (DUB) inhibitor that affects type I IFNs and NF-κB induced by poly(I:C).*The compound is unstable in solutions, freshly prepared is recommended |
| M5191 | C-DIM12 | C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells. |
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