| Cat.No. | Name | Information |
|---|---|---|
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M13510 | Hematoporphyrin dihydrochloride | Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. |
| M13509 | GPNA hydrochloride | GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). |
| M13508 | Geranyl acetate | Geranyl acetate, an acyclic monoterpene ester derived from geraniol, is widely used in the cosmetics industry due to its pleasant scent. Geranyl acetate can induces cell apoptosis. |
| M13507 | Furanodienone | Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis. |
| M13506 | Formosanin C | Formosanin C is a diosgenin saponin isolated from Paris formosana Hayata and an immunomodulator with antitumor activity. Formosanin C induces apoptosis. |
| M13502 | Demethoxycurcumin | Demethoxycurcumin(Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis. |
| M13501 | Bufotalin | Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation. |
| M13500 | Bisdemethoxycurcumin | Bisdemethoxycurcumin (BDMC; Curcumin III) is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities. |
| M13498 | Adarotene | Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells. |
| M13379 | Guggulsterone | Guggulsterone is a plant sterol from the gum fat of the Commiphora Wightii tree. Guggulsterone is a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC50s of 17 and 15 μM for Z- and E-Guggulsterone, respectively. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. |
| M11366 | Se-Methylselenocysteine | Se-methylselenocysteine, a precursor of methyl selenium, has strong cancer chemoprophylaxis and antioxidant activity. Se-Methylselenocysteine has oral biological activity, can induce apoptosis. |
| M11334 | Levomenol | Levomenol ((-)-α -bisabolol) isa monocyclic sesquiterpenoid alcohol with antioxidant, anti-inflammatory and anti-apoptotic effects. Levomenol also has neuroprotective effects, preventing neuronal damage and memory deficits by reducing pro-inflammatory markers of permanent focal cerebral ischemia induction in mice. Levomenol reduces nociceptive behavior and central sensitivity in a rodent model of trigeminal pain. |
| M11210 | MN58b | MN58b is a selective inhibitor of choline kinase α (CHKα) and inhibits phosphocholine synthesis. MN58b induces apoptosis to reduce cell growth. MN58b also has antitumoral activity. |
| M11195 | CDDO-2-P-Im | Cddo-2p-im is a CDDO imidazolid analogue with chemoprophylaxis. Cddo-2p-im reduced the size and severity of lung tumors in mouse lung cancer models. Cddo-2p-im is an orally active necroptosis inhibitor that can be used in ischemia/reperfusion (I/R) studies. |
| M11194 | CDDO-3-P-Im | Cddo-3p-im is a CDDO imidazolid analogue with chemoprophylaxis. Cddo-3p-im can reduce the size and severity of lung tumors in mouse lung cancer models. |
| M11178 | Taurochenodeoxycholic acid | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animal bile acids. Taurochenodeoxycholic acid induces apoptosis (apoptosis) and has a pronounced anti-inflammatory and immunomodulatory effect. |
| M11093 | Ranaconitine | Ranaconitine is a diterpene alkaloid isolated from A. leucostomum and is cardiotoxic. |
| M11090 | Dihydrocucurbitacin B | Dihydrocucurbitacin B is a triterpenoid in the tariae root that inhibits the activation of T-cell nuclear factors, induces arrest in the G0 phase of the cell cycle, and inhibits delayed hypersensitivity reactions. |
| M11001 | COG-1410 TFA | COG1410 is a peptide derived from apolipoprotein E. COG1410 plays a neuroprotective and anti-inflammatory role in a mouse brain injury (TBI) model. COG1410 can be used in the study of neurological diseases. |
| M10998 | Soyasapogenol A | Soyasapogenol A, a triterpenoid compound isolated from the roots of Abrus cantoniensis. |
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