| Cat.No. | Name | Information |
|---|---|---|
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M13512 | Kinetin riboside | Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM. |
| M13505 | Ethoxysanguinarine | Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A). |
| M13503 | EC359 | EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions. |
| M13402 | Deoxynyboquinone | Deoxynyboquinone is a potent inducer of cancer cell death with IC(50) values between 16 and 210 nM. |
| M11450 | Chaetoglobosin A | Chaetoglobosin A is an active ingredient in the extract of Penicillium aquamarinium and A member of cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells, thereby inducing cell cycle arrest and inhibiting membrane folds and cell migration. |
| M11170 | NSC745885 | NSC745885 is a potent anti-tumor reagent that is selectively toxic to a variety of cancer cell lines but not to normal cells. NSC745885 is a potent downregulator of EZH2 through the proteasome degradation pathway. NSC745885 offers the possibility of research on advanced bladder cancer and oral squamous cell carcinoma. |
| M11048 | Isolongifolene | Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene mitigates rotenone-induced oxidative stress, mitochondrial dysfunction, and apoptosis by modulating the PI3K/AKT/GSK-3β signaling pathway. |
| M11040 | AMXT-1501 tetrahydrochloride | AMXT-1501 tetrahydrochloride is an orally active polyamine transport inhibitor. AMXT-1501 blocks tumor growth in immunocompetent mice, but not T cell-deficient thymic nude mice. DFMO and AMXT-1501 jointly induce caspase-3-mediated apoptosis of NB cells. |
| M8335 | NCX 4040 | NCX4040 (NO-Aspirin) is a nitric oxide-donating form of aspirin, and a non-steroidal anti-inflammatory agent. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. |
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