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Apoptosis Apoptosis related

Cat.No.  Name Information
M9075 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt.
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M13520 Ro 08-2750 Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM.
M13519 Rhapontin Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells.
M13517 Polygalacin D Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum (Jacq.) with anticancer and anti-proliferative properties.
M13515 Periplocin Periplocin is a cardiotonic steroid isolated from Periploca forrestii.
M13513 Naphthazarin Naphthazarin (DHNQ) is a naturally occurring compound.
M13512 Kinetin riboside Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM.
M13508 Geranyl acetate Geranyl acetate, an acyclic monoterpene ester derived from geraniol, is widely used in the cosmetics industry due to its pleasant scent. Geranyl acetate can induces cell apoptosis.
M13507 Furanodienone Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis.
M13505 Ethoxysanguinarine Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A).
M13503 EC359 EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions.
M13502 Demethoxycurcumin Demethoxycurcumin(Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.
M13402 Deoxynyboquinone Deoxynyboquinone is a potent inducer of cancer cell death with IC(50) values between 16 and 210 nM.
M11450 Chaetoglobosin A Chaetoglobosin A is an active ingredient in the extract of Penicillium aquamarinium and A member of cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells, thereby inducing cell cycle arrest and inhibiting membrane folds and cell migration.
M11170 NSC745885 NSC745885 is a potent anti-tumor reagent that is selectively toxic to a variety of cancer cell lines but not to normal cells. NSC745885 is a potent downregulator of EZH2 through the proteasome degradation pathway. NSC745885 offers the possibility of research on advanced bladder cancer and oral squamous cell carcinoma.
M11048 Isolongifolene Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene mitigates rotenone-induced oxidative stress, mitochondrial dysfunction, and apoptosis by modulating the PI3K/AKT/GSK-3β signaling pathway.
M11040 AMXT-1501 tetrahydrochloride AMXT-1501 tetrahydrochloride is an orally active polyamine transport inhibitor. AMXT-1501 blocks tumor growth in immunocompetent mice, but not T cell-deficient thymic nude mice. DFMO and AMXT-1501 jointly induce caspase-3-mediated apoptosis of NB cells.




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