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Omigapil maleate

Cat. No. M29097

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Omigapil maleate Structure
Synonym:

CGP3466B; CGP3446 maleate; TCH346 maleate

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Quality Control & Documentation
Biological Activity

Omigapil maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).

Chemical Information
Molecular Weight 391.42
Formula C23H21NO5
CAS Number 200189-97-5
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C)
Storage 4°C, dry, sealed
References

[1] Trevor V Gale, et al. J Proteome Res. Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors

[2] P C Waldmeier, et al. Naunyn Schmiedebergs Arch Pharmacol. CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease

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Keywords: Omigapil maleate, CGP3466B; CGP3446 maleate; TCH346 maleate supplier, Apoptosis, inhibitors, activators

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