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Apoptosis Apoptosis related

Cat.No.  Name Information
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M9075 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt.
M54729 Alginic acid Alginic acid is a naturally occurring polysaccharide that induces oxidative stress-mediated hormone disruption, apoptosis and autophagy in mouse granulosa cells and ovaries, and inhibits histamine release. In addition, Alginic acid has good water solubility, film-forming, biodegradable and biocompatible properties, as well as anti-allergic and anti-inflammatory activities.
M54627 Cytochrome C (from Pig Heart) Cytochrome C (from Pig Heart) is a multifunctional enzyme involved in cellular life and death decisions.Cytochrome C is critical in mitochondrial electron transport and intrinsic type II apoptosis.
M54584 Celosin K Celosin K, a triterpenoid saponin isolated from the seeds of Semen Celosiae, is also a potent inhibitor of t-BHP-induced neuronal damage. In addition, Celosin K inhibits oxidative stress, apoptosis, and autophagy.
M45007 Sodium taurochenodeoxycholate Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid.
M44809 Cinchonine hydrochloride Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity.
M40997 CWI1-2 hydrochloride CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity.
M40996 CWI1-2 CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity.
M38828 Alphitolic acid Alphitolic acid (Aophitolic acid) blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research.
M38823 Phytosphingosine Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells.
M31179 12-HETE 12-HETE is a metabolite of arachidonic acid catalyzed by lipoxygenase (12-LOX). It is also a highly selective ligand that can be used to label mu opioid receptors in membrane and tissue sections. In addition, 12-HETE functions as an inhibitor of apoptosis.
M31154 Mimosine Mimosine is a known chelator of Fe(III), induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells. Mimosine can act as an antioxidant by its potent iron-binding activity.
M31123 Necroptosis-IN-3 Necroptosis-IN-3, an inhibitor of necroptosis, inhibits TNF-α-induced necroptosis and also inhibits 11β-HSD1.
M30986 Citicoline Citicoline (Cytidine diphosphate-choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
M29323 DB2313  DB2313 is a potent transcription factor PU.1 inhibitor with an apoptosis of 14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects.
M25302 FG-3019 FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF).
M22524 Dihydrorotenone Dihydrorotenone is a potent mitochondrial inhibitor. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway.
M21662 MGH-CP1 MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells.
M21648 PDK4-IN-1 hydrochloride PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis.




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