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Apoptosis Apoptosis related

Cat.No.  Name Information
M9075 Etomoxir sodium salt Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M18527 Ganoderic acid DM Ganoderic acid DM is a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis.
M18292 4-Hydroxybenzyl alcohol 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants, with anti-inflammatory, anti-oxidant, anti-nociceptive activity.
M18267 3-O-Acetyloleanolic acid 3-O-Acetyloleanolic acid
M18178 3-oxo-urs-12-en-28-oic acid 3-oxo-urs-12-en-28-oic acid
M17797 Quillaic acid Quillaic acid is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. Quillaic acid also has analgesic and local anti-inflammatory activity.
M16932 (+)-Pinoresinol (+)-Pinoresinol is a lignol which drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis.
M16778 Gardenin B Gardenin B is a flavonoid isolated from Gardenia jasminoides. Gardenin B induces cell death in human leukemia cells involves multiple caspases.
M16777 Salvigenin Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis.
M16760 Kumatakenin Kumatakenin is a flavonoid isolated from cloves, which shows the effect of inducing apoptosis in ovarian cancer cells.
M16672 Sophoraflavanone G Sophoraflavanone G induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. Sophoraflavanone G (Kushenol F) shows anti-tumor and anti-inflammatory properties.
M16525 Pinusolide Pinusolide is a known platelet-activating factor (PAF) receptor binding antagonist. Pinusolide not only decreases the proliferation activity of tumor cells but specifically induces apoptosis.
M16194 Boldine Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research.
M15094 Bromelain Bromelain, an anti-inflammatory compound derived from pineapple stem, acts by down-regulating plasma kinkinin, inhibiting prostaglandin E2 expression, degradation of receptors for advanced glycation end products, regulation of angiogenic biomarkers, and antioxidant activity upstream of the COX pathway. Can be used as a food additive.
M14658 Barbadin Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2.
M13522 Sophoridine Sophoridine is a quinolizidine alkaloid isolated from leafs of Leguminous plant Sophora alopecuroides.L.
M13521 Sesamol Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities. Anticancer activities.
M13519 Rhapontin Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baillon), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells.
M13518 Poncirin Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models.
M13514 Neobavaisoflavone Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia.
M13511 Iberin Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC50 of 2.3 μM in HL60 cell. Iberin induces apoptosis.




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