Cat.No. | Name | Information |
---|---|---|
M9075 | (R)-(+)-Etomoxir sodium salt | (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt. |
M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
M11090 | Dihydrocucurbitacin B | Dihydrocucurbitacin B is a triterpenoid in the tariae root that inhibits the activation of T-cell nuclear factors, induces arrest in the G0 phase of the cell cycle, and inhibits delayed hypersensitivity reactions. |
M11001 | COG-1410 | COG1410 is a peptide derived from apolipoprotein E. COG1410 plays a neuroprotective and anti-inflammatory role in a mouse brain injury (TBI) model. COG1410 can be used in the study of neurological diseases. |
M10998 | Soyasapogenol A | Soyasapogenol A, a triterpenoid compound isolated from the roots of Abrus cantoniensis. |
M10997 | 3'-Hydroxypterostilbene | 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC for COLO 205, HCT-116 and HT-29 cells) by inducing apoptosis (apoptosis) and autophagy50 9.0, 40.2 and 70.9 μM, respectively). |
M10969 | NSC 15364 | NSC 15364 is a VDAC1 oligomerization and apoptosis inhibitor. |
M10967 | Coenzyme Q9 | Coenzyme Q9 (Ubiquinone Q9), the main form of rodent ubiquinone, is a biparent molecular component in the electron transport chain that acts as an endogenous antioxidant. Coenzyme Q9 mitigates a decline in antioxidant defense mechanisms caused by diabetes. Coenzyme Q9 improves left ventricular function, reduces myocardial infarction area and apoptosis of myocardial cells. |
M10761 | DC260126 | DC260126 is a potent GPR40 (FFAR1) antagonist. DC260126 dose-dependent inhibits GPR40-mediated Ca of linoleic acid, oleic acid, palm oleic acid, and lauric acid irritation2+ ELEVATED (IC50 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 is protective of palmitate-induced endoplasmic reticulum stress and apoptosis ( apoptosis ) . |
M10757 | Flavokawain B | Flavokawain B (Flavokavain B) is a chalcone isolated from the root extract of kava drunken pepper and is an effective apoptotic inducer that inhibits the growth of various cancer cell lines. (Flavokavain B) has strong anti-angiogenic activity. (Flavokavain B) inhibits the migration and vascular formation of human brain endothelial cells (HUVEC) at very low non-toxic concentrations. |
M10756 | Flavokawain A | Flavokawain A is an anticarcinogenic agent, a chalcone found in kava extracts with antitumor activity. Flavokawain A induces apoptosis through Bax protein-dependent and mitochondrial-dependent apoptosis pathways. Flavokawain A has the potential to be used in bladder cancer related research. |
M10674 | Prosapogenin A | Prosapogenin A is a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis. |
M10673 | Procyanidin C1 | Procyanidin C1 (PCC1) is a natural polyphenol, which causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. |
M10672 | Thonningianin A | Thonningianin A is an ellagitannin with anti-cancer activities. Thonningianin A also has antioxidant properties of radical scavenging, anti-superoxide formation and metal chelation. |
M10671 | Garcinone E | Garcinone E is the most active xanthone from mangosteen, which has potent cytotoxic effect against hepatocellular carcinoma cell lines. Garcinone E might inhibit metastasis of an oral cancer cell line by blocking invasion, migration and MMP production. |
M10607 | NUN82647 (CU-242) | NUN82647 (2-Amino-N-quinolin-8-yl-benzenesulfonamide, QBS, CU-242) is an inhibitor of cell cycle at G2 phase; it is also an apoptosis inducer. |
M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
M10165 | TPEN | TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. |
M9940 | Unesbulin(PTC596) | PTC596 is a novel BMI-1 inhibitor, downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. |
M9477 | NSC348884 | NSC348884 is a nucleophosmin (NPM) inhibitor that also disrupts oligomer formation as well as induces apoptosis, with an IC50 of 1.7-4.0 μM for inhibition of proliferation in different cancer cell lines.Can be used in cancer-related studies. |
M9319 | Dimethyl anthranilate | Dimethyl anthranilate is widely used in the preparation of flavours. |
M8686 | CCF642 | CCF642 is a cell-permeable protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action that most likely involves PDI active-site CGHCK motifs instead of cysteine known to be targeted by PACMA 31. |
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