| Cat.No. | Name | Information |
|---|---|---|
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M10997 | 3'-Hydroxypterostilbene | 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC for COLO 205, HCT-116 and HT-29 cells) by inducing apoptosis (apoptosis) and autophagy50 9.0, 40.2 and 70.9 μM, respectively). |
| M10969 | NSC 15364 | NSC 15364 is a VDAC1 oligomerization and apoptosis inhibitor. |
| M10967 | Coenzyme Q9 | Coenzyme Q9 (Ubiquinone Q9), the main form of rodent ubiquinone, is a biparent molecular component in the electron transport chain that acts as an endogenous antioxidant. Coenzyme Q9 mitigates a decline in antioxidant defense mechanisms caused by diabetes. Coenzyme Q9 improves left ventricular function, reduces myocardial infarction area and apoptosis of myocardial cells. |
| M10761 | DC260126 | DC260126 is a potent GPR40 (FFAR1) antagonist. DC260126 dose-dependent inhibits GPR40-mediated Ca of linoleic acid, oleic acid, palm oleic acid, and lauric acid irritation2+ ELEVATED (IC50 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 is protective of palmitate-induced endoplasmic reticulum stress and apoptosis ( apoptosis ) . |
| M10757 | Flavokawain B | Flavokawain B (Flavokavain B) is a chalcone isolated from the root extract of kava drunken pepper and is an effective apoptotic inducer that inhibits the growth of various cancer cell lines. (Flavokavain B) has strong anti-angiogenic activity. (Flavokavain B) inhibits the migration and vascular formation of human brain endothelial cells (HUVEC) at very low non-toxic concentrations. |
| M10756 | Flavokawain A | Flavokawain A is an anticarcinogenic agent, a chalcone found in kava extracts with antitumor activity. Flavokawain A induces apoptosis through Bax protein-dependent and mitochondrial-dependent apoptosis pathways. Flavokawain A has the potential to be used in bladder cancer related research. |
| M10674 | Prosapogenin A | Prosapogenin A is a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis. |
| M10673 | Procyanidin C1 | Procyanidin C1 (PCC1) is a natural polyphenol, which causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. |
| M10672 | Thonningianin A | Thonningianin A is an ellagitannin with anti-cancer activities. Thonningianin A also has antioxidant properties of radical scavenging, anti-superoxide formation and metal chelation. |
| M10671 | Garcinone E | Garcinone E is the most active xanthone from mangosteen, which has potent cytotoxic effect against hepatocellular carcinoma cell lines. Garcinone E might inhibit metastasis of an oral cancer cell line by blocking invasion, migration and MMP production. |
| M10607 | NUN82647 (CU-242) | NUN82647 (2-Amino-N-quinolin-8-yl-benzenesulfonamide, QBS, CU-242) is an inhibitor of cell cycle at G2 phase; it is also an apoptosis inducer. |
| M10320 | Chondroitin sulfate | Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. |
| M10165 | TPEN | TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. |
| M9940 | Unesbulin | Unesbulin (PTC596) is a novel orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) inhibitor, Unesbulin downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. |
| M9649 | Lobaplatin | Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent. Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. |
| M9477 | NSC348884 | NSC348884 is a nucleophosmin (NPM) inhibitor that also disrupts oligomer formation as well as induces apoptosis, with an IC50 of 1.7-4.0 μM for inhibition of proliferation in different cancer cell lines.Can be used in cancer-related studies. |
| M9319 | Dimethyl anthranilate | Methyl N-methylanthranilate is a pungent compound that can be found in Citrus reticulate Blanco leaves. Dimethyl anthranilate is widely used in the preparation of flavours. |
| M8686 | CCF642 | CCF642 is a cell-permeable protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action that most likely involves PDI active-site CGHCK motifs instead of cysteine known to be targeted by PACMA 31. |
| M8392 | Tirapazamine | Tirapazamine (TPZ，SR-4233, WIN 59075) is the first hypoxia-activated prodrug. Tirapazamine kills hypoxic cells by inducing chromosome aberrations and DNA double-strand breaks. Tirapazamine induced cell cycle arrest and apoptosis, and down-regulated HIF-1α, CA-IX and VEGF expression. |
| M8258 | KYP-2047 | KYP-2047 is a potent and BBB-penetrating prolyl-oligopeptidase (POP) inhibitor, with an Ki value of 0.023 nM. KYP-2047 reduces glioblastoma proliferation through angiogenesis and apoptosis modulation. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
