| Cat.No. | Name | Information |
|---|---|---|
| M9075 | Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. |
| M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
| M5298 | NSC-144303 | Ubiquitin Isopeptidase Inhibitor I, G5 (NSC-144303) is a broad-spectrum cell-permeable deubiquitinating enzyme (DUB) inhibitor that affects type I IFNs and NF-κB induced by poly(I:C).*The compound is unstable in solutions, freshly prepared is recommended |
| M5191 | C-DIM12 | C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells. |
| M4971 | Azoramide | Azoramide is a potent, orally active small-molecule modulator of the unfolded protein response (UPR). Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. |
| M4757 | 1,2,3,4,6-pentagalloylglucose | 1,2,3,4,6-pentagalloylglucose (Pentagalloylglucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. |
| M4743 | Jolkinolide-B | Jolkinolide B is a diterpenoid with biological activity isolated from euphorbia officinalis root. It is known that Jolkinolide B can induce apoptosis of cancer cells. |
| M4739 | Notopterol | Notopterol is coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, pain-relieving and anti-inflammatory effects. Notopterol has potential for use in acute myeloid leukemia (AML). |
| M4688 | Momordin-Ic | Momordin-Ic is a SENP1 Inhibitor. Momordin Ic induces apoptosis through oxidative stress-regulated mitochondrial dysfunction. |
| M4683 | Sclareol | Sclareol was isolated from Salvia sclarea and showed anticancer activity. Sclareol has strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB), and human white blood cells. Sclareol can induce apoptosis. |
| M4668 | Astragalin | Astragalin (kaempferol-3-O-glucoside) is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds. |
| M4580 | Cyclovirobuxine | Cyclovirobuxine D (CVB-D) is the main active ingredient of Buxus microphylla. Cyclovirobuxine D induces autophagy and reduces Akt and mTOR phosphorylation. Cyclovirobuxine D inhibits the proliferation of cancer cells by inhibiting cell cycle progression and inducing mitochondria - mediated apoptosis. Cyclovirobuxine D has the potential to be used in the study of heart failure caused by myocardial infarction. |
| M4564 | Lobetyolin | Lobetyolin is a bioactive compound isolated from Codonopsis Pilosula. Lobetyolin has anti-inflammatory, antioxidant and xanthine oxidase inhibitory activities. Lobetyolin also induces apoptosis by inhibiting ASCT2-mediated glutamine metabolism. |
| M4559 | Ziyuglycoside-II | Ziyuglycoside II from Sanguisorba officinalis L. Triterpenoid saponins extracted from the. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. It has anti-inflammatory and anticancer effects. |
| M4557 | Dictamine | Dictamnine (Dictamine) is cytotoxic to human cervical and colon cancer cells, and also has antibacterial and antifungal activities. |
| M4526 | Benzoylpaeoniflorin | Benzoylpaeoniflorin, a natural compound extracted from paeonia lactiflora, has the potential to be used in the study of coronary heart disease by reducing apoptosis. |
| M4511 | Tectorigenin | Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. |
| M4508 | Madecassoside | Madecassoside is an anti-inflammatory pentacyclic triterpenoid isolated from a large bowl. Antioxidant and anti-aging effects. |
| M4496 | Linderalactone | Linderalactone is an important sesquiterpene lactone isolated from Radix Linderae. Linderalactone inhibits cancer cell growth by regulating the expression of apoptosis-related proteins and inhibiting the JAK/STAT signaling pathway. Linderalactone also inhibited the proliferation of lung cancer A-549 cells with an IC50 value of 15 µM. |
| M4492 | Curcurbitacin-Iib | Cucurbitacin IIb is the active ingredient in chorioides, which induces apoptosis and has anti-inflammatory activity. Cuc |
| M4490 | Protosappanin-B | Protosappanin B is a polyphenol substance extracted from Sappanwood, which has anti-tumor effect. In human bladder cancer cells, it can induce apoptosis by arresting G1 phase of cell cycle. |
| M4477 | Costunlide | Costunlide |
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