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8-Prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice.
| Molecular Weight | 340.37 |
| Formula | C20H20O5 |
| CAS Number | 53846-50-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage | 4°C, protect from light |
[3] Judy L Bolton, et al. The Multiple Biological Targets of Hops and Bioactive Compounds
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