About 4 results found for searched term "8-Prenylnaringenin" (1.262 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5173 | 8-Prenylnaringenin | Apoptosis |
| 8-Prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. | ||
| M16606 | 6-Methyl-8-prenylnaringenin | Flavonoids |
| 6-Methyl-8-prenylnaringenin | ||
| M30477 | 6,8-Diprenylnaringenin | BCRP/ABCG2/MXR/ABCP |
| Lonchocarpol A; Senegalensin | ||
| 6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin. | ||
| M30486 | (±)-8-Prenylnaringenin | Estrogen Receptor |
| (±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM, respectively. (±)-8-Prenylnaringenin has anticancer effects, and can be used for osteoporosis research. | ||
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