Dictamine

Cat. No. M4557

All AbMole products are for research use only, cannot be used for human consumption.

Synonym:

Dictamnine; Dectamine

Size	Price	Availability	Quantity
20mg	USD 200 USD200	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Dictamnine (Dictamine) is cytotoxic to human cervical and colon cancer cells, and also has antibacterial and antifungal activities.

	Source	Asian Pac J Cancer Prev (2013). Figure 3. Dictamine
	Method	Apoptosis assay
	Cell Lines	A549 cell line
	Concentrations	300 and 500 μM
	Incubation Time	24 h
	Results	However, after exposure to 300 and 500 μM Dic for 24 h, cells with typical morphologic changes of apoptosis that chromatin condensation and shrunken nucleus (Figure 3B and C) were increased.

	Source	Asian Pac J Cancer Prev (2013). Figure 1. Dictamine
	Method	CCK-8 Assay
	Cell Lines	A549 cell line
	Concentrations	100, 300 and 500 μM
	Incubation Time	24 and 48 h
	Results	Moreover, the results that A549 cells treated with 300 μM Dic for different times (8, 12, 18 and 24 h) demonstrated that Dic induced A549 cells death in a time-dependent manner

Cell Experiment
Cell lines	A549 cell
Preparation method	Cell cycle distribution was analyzed using FCM. Briefly, after cells were treated with 300 and 500 μM Dic for 24 h, the cells were harvested, washed twice with PBS, and fixed in 70 % ethanol at 4 °C for 1 h and centrifuged.
Concentrations	300 and 500 μM
Incubation time	24 h

Molecular Weight	199.21
Formula	C12H9NO2
CAS Number	484-29-7
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related Apoptosis Products
Coenzyme Q0 Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of inflammation and redox imbalance.
C6 Ceramide C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway.
DB2115 tertahydrochloride DB2115 tertahydrochloride is a potent inhibitor of myeloid master regulator PU.1. DB2115 tertahydrochloride has the potential for researching cancers, including hematologic cancers.
14-3-3η Protein inhibitor 1 14-3-3η Protein inhibitor 1 is a 14-3-3η protein inhibitor with a KD of 35 µM.
Deferoxamine Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.

Catalog