Cat.No. | Name | Information |
---|---|---|
M10566 | Valepotriate | Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones. |
M9075 | (R)-(+)-Etomoxir sodium salt | (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt. |
M54627 | Cytochrome C (from Pig Heart) | Cytochrome C (from Pig Heart) is a multifunctional enzyme involved in cellular life and death decisions.Cytochrome C is critical in mitochondrial electron transport and intrinsic type II apoptosis. |
M54584 | Celosin K | Celosin K, a triterpenoid saponin isolated from the seeds of Semen Celosiae, is also a potent inhibitor of t-BHP-induced neuronal damage. In addition, Celosin K inhibits oxidative stress, apoptosis, and autophagy. |
M45007 | Sodium taurochenodeoxycholate | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. |
M44809 | Cinchonine hydrochloride | Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. |
M40997 | CWI1-2 hydrochloride | CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity. |
M40996 | CWI1-2 | CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity. |
M38828 | Alphitolic acid | Alphitolic acid (Aophitolic acid) blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research. |
M38824 | Kuguaglycoside C | Kuguaglycoside C is a triterpene glycoside that induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF). |
M38823 | Phytosphingosine | Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells. |
M31179 | 12-HETE | 12-HETE is a metabolite of arachidonic acid catalyzed by lipoxygenase (12-LOX). It is also a highly selective ligand that can be used to label mu opioid receptors in membrane and tissue sections. In addition, 12-HETE functions as an inhibitor of apoptosis. |
M31154 | Mimosine | Mimosine is a known chelator of Fe(III), induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells. Mimosine can act as an antioxidant by its potent iron-binding activity. |
M31123 | Necroptosis-IN-3 | Necroptosis-IN-3, an inhibitor of necroptosis, inhibits TNF-α-induced necroptosis and also inhibits 11β-HSD1. |
M30986 | Citicoline | Citicoline (Cytidine diphosphate-choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects. |
M29569 | SU056 | SU056 is a YB-1 inhibitor. SU056 induces cell-cycle arrest, apoptosis, and inhibits cell migration in ovarian cancer cells. SU056 interacts with YB-1 and inhibits and its associated downstream proteins and pathways. SU056 can enhance the cytotoxic effects of Paclitaxel. |
M29323 | DB2313 | DB2313 is a potent transcription factor PU.1 inhibitor with an apoptosis of 14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects. |
M28054 | Minnelide | Minnelide is a precursor of triptolide that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide promotes apoptosis. |
M25302 | FG-3019 | FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF). |
M22524 | Dihydrorotenone | Dihydrorotenone is a potent mitochondrial inhibitor. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. |
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