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Chondroitin sulfate

Cat. No. M10320

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Chondroitin sulfate Structure
Synonym:

Chondroitin polysulfate; Chonsurid

Size Price Availability Quantity
250mg USD 40  USD40 In stock
500mg USD 60  USD60 In stock
1g USD 75  USD75 In stock
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Quality Control & Documentation
Biological Activity

Chondroitin sulfate is a class of sulfated glycosaminoglycans that are linear polysaccharides consisting of repeating disaccharide units composed of uronic acid and N-acetylhexosamine, which has been widely used in the treatment of osteoarthritis. Chondroitin sulfate (200 mg/mL) decreases the chondrocyte susceptibility to single nucleotide polymorphism-induced apoptosis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS, MMPs.

Chemical Information
Formula (C14H21NO14S)n
CAS Number 9007-28-7
Solubility (25°C) Water ≥ 50 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Johanne Martel-Pelletier, et al. Molecules. Discrepancies in composition and biological effects of different formulations of chondroitin sulfate

[2] Tadahisa Mikami, et al. Biochim Biophys Acta. Biosynthesis and function of chondroitin sulfate

[3] Yves Henrotin, et al. Ther Adv Musculoskelet Dis. Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations

[4] Giuseppe M Campo, et al. J Cell Biochem. Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes

[5] J Monfort, et al. Ann Rheum Dis. Biochemical basis of the effect of chondroitin sulphate on osteoarthritis articular tissues

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Keywords: Chondroitin sulfate, Chondroitin polysulfate; Chonsurid supplier, Apoptosis, inhibitors, activators

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