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Apoptosis Apoptosis related

Cat.No.  Name Information
M9075 Etomoxir sodium salt Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M55857 Oxythiamine chloride hydrochloride Oxythiamine (Hydroxythiamine) chloride hydrochloride, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis.
M55643 SKLB-163 SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis.
M55394 T-2 Toxin T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides.
M54495 GLP-2(rat) GLP-2(rat) is an intestinal growth factor.
M54364 Edratide Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id.
M54262 Thrombospondin-1 (1016-1023) (human, bovine, mouse) Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide.
M54140 ABT-510 acetate ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer.
M53429 Bax BH3 peptide (55-74), wild type Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models.
M53428 NTR 368 NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor.
M53427 (Gly14)-Humanin (human) (Gly14)-Humanin (human) (14-Glycine-Humanin (human)) is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly).
M53426 Tumor targeted pro-apoptotic peptide Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide.
M53425 Argipressin diacetate Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary.
M53424 WLSEAGPVVTVRALRGTGSW WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide.
M53423 Ac-IETD-CHO Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase-8.
M53422 Amyloid 17-42 Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP).
M53421 Malformin A1 Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity.
M53420 Fexapotide Fexapotide (NX-1207 free acid) induces apoptosis selectively, reducing prostate volume at a cellular level.
M53419 Tigapotide Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer.
M53418 cpm-1285 cpm-1285 induces apoptosis by functionally blocking intracellular Bcl-2 and related death antagonists.
M53417 ABT-510 ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer.




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