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Azadirachtin

Cat. No. M18864

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Azadirachtin Structure
Size Price Availability Quantity
5mg USD 270  USD270 In stock
10mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation).

Chemical Information
Molecular Weight 720.71
Formula C35H44O16
CAS Number 11141-17-6
Solubility (25°C) DMSO 70 mg/mL
Storage -20°C, protect from light
References

[1] Ji-Bing He, et al. Exp Biol Med (Maywood). Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats

[2] Nadia Aribi, et al. Med Sci (Paris). [Azadirachtin, a natural pesticide with multiple effects]

[3] Tianyi Zhao, et al. Ecotoxicol Environ Saf. Azadirachtin A inhibits the growth and development of Bactrocera dorsalis larvae by releasing cathepsin in the midgut

[4] Teesta V Katte, et al. J Basic Clin Physiol Pharmacol. Assessment of azadirachtin-A, a neem tetranortritarpinoid, on rat spermatozoa during in vitro capacitation

[5] E David Morgan. Bioorg Med Chem. Azadirachtin, a scientific gold mine

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Keywords: Azadirachtin supplier, Apoptosis, inhibitors, activators

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