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RIPGBM 

Cat. No. M29971

All AbMole products are for research use only, cannot be used for human consumption.

RIPGBM  Structure

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Quality Control & Documentation
Biological Activity

RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme (GBM) cancer stem cells (CSCs) with an EC50 of ≤500 nM.

Chemical Information
Molecular Weight 428.45
Formula C26H21FN2O3
CAS Number 355406-76-7
Form Solid
Solubility (25°C) DMSO 33.33 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Thomas J West, et al. J Am Chem Soc. A Cell Type Selective YM155 Prodrug Targets Receptor-Interacting Protein Kinase 2 to Induce Brain Cancer Cell Death

[2] Natasha C Lucki, et al. Proc Natl Acad Sci U S A. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer

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Keywords: RIPGBM  supplier, Apoptosis, inhibitors, activators

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