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iMAC2

Cat. No. M6822

All AbMole products are for research use only, cannot be used for human consumption.

iMAC2 Structure

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Quality Control & Documentation
Biological Activity

iMAC2 is a inhibitor of mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM). Reduces STS-induced apoptosis in FL5.12 cells by over 50%. Inhibits release of cytochrome c by Bid-induced Bax activation (IC50 = 0.68 μM).

Chemical Information
Molecular Weight 542.11
Formula C19H20Br2FN3.2HCl
CAS Number 335166-00-2
Solubility (25°C) DMSO 2.71 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bubenik. J Physiol Pharmacol. Thirty four years since the discovery of gastrointestinal melatonin.

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Keywords: iMAC2 supplier, inhibitors, activators

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