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Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy. Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Mice treated with 20 and 40 mg/kg Ginsenoside Rh4 and 40 mg/kg CAMPTO exhibit smaller tumors than the control after 30 days of treatment, showing inhibition rates of 29.91%, 66.30% and 77.82%, respectively. However, there is a significant difference in body weight between the Ginsenoside Rh4-treated group and the CAMPTO-treated group.
| Molecular Weight | 620.86 |
| Formula | C36H60O8 |
| CAS Number | 174721-08-5 |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage | -20°C, sealed |
[1] Xueni Niu, et al. Nat Prod Res. Two new dammarane-type ginsenosides from Panax ginseng
[5] Qi-le Zhou, et al. Zhongguo Zhong Yao Za Zhi. [Chemical constituents of Chinese red ginseng]
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