About 30 results found for searched term "Chloride Channel" (0.046 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2181 | ML133 hydrochloride | Potassium Channel |
| ML133 HCl | ||
| ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels. | ||
| M2620 | Dequalinium Chloride | PKC |
| Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM. | ||
| M2632 | Dibucaine hydrochloride | Animal experimental anesthetics |
| Cinchocaine HCl | ||
| Dibucaine (Cinchocaine) hydrochloride is a sodium channel inhibitor. Dibucaine hydrochloride is a potent SChE inhibitor. Dibucaine hydrochloride is a local anesthetics. | ||
| M2649 | Doxapram hydrochloride hydrate | Potassium Channel |
| Doxapram HCl | ||
| Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. | ||
| M2810 | Levobupivacaine hydrochloride | Animal experimental anesthetics |
| (S)-(-)-Bupivacaine monohydrochloride | ||
| Levobupivacaine hydrochloride is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. | ||
| M2820 | Lomerizine dihydrochloride | Calcium Channel |
| KB-2796 | ||
| Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine. | ||
| M2847 | Mexiletine hydrochloride | Sodium Channel |
| Mexiletine hydrochloride belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current. | ||
| M2877 | Nefopam hydrochloride | Wnt/beta-catenin |
| Fenazoxine hydrochloride | ||
| Nefopam hydrochloride is an centrally-acting but non-opioid analgesic compound by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake. | ||
| M3080 | Tolperisone hydrochloride | Others |
| Tolperisone hydrochloride is an ion channel blocker and centrally-acting muscle relaxant. | ||
| M3118 | Verapamil hydrochloride | Calcium Channel |
| (±)-Verapamil hydrochlorid | ||
| Verapamil hydrochloride (VPH) is an orally active L-type calcium channel inhibitor that eliminates calcium channel agonist-induced calcium inward flow and apoptosis. Verapamil hydrochloride is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. | ||
| M3210 | Benidipine hydrochloride | Calcium Channel |
| KW-3049 | ||
| Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. | ||
| M3296 | Manidipine dihydrochloride | Calcium Channel |
| CV-4093 | ||
| Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4. | ||
| M3358 | Procainamide hydrochloride | Sodium Channel |
| Procaine amide hydrochloride; SP 100 hydrochloride | ||
| Procainamide hydrochloride is a sodium channel blocker, and also a DNA methyltransferase inhibitor. | ||
| M3365 | Tetracaine hydrochloride | Calcium Channel |
| Amethocaine hydrochloride | ||
| Tetracaine hydrochloride is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. | ||
| M3366 | Amiloride hydrochloride dihydrate | Sodium Channel |
| MK-870 hydrochloride dihydrate | ||
| Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. | ||
| M3386 | Amiloride hydrochloride | Sodium Channel |
| MK-870 hydrochloride | ||
| Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. | ||
| M3418 | Bupivacaine hydrochloride | Animal experimental anesthetics |
| Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain. | ||
| M3456 | Chlorpromazine hydrochloride | Potassium Channel |
| Sonazine | ||
| Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine also excites the 20S proteasome. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M3500 | Diltiazem hydrochloride | Calcium Channel |
| CRD-401 | ||
| Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases. | ||
| M4633 | Atractyloside | Chloride Channel |
| Atractyloside potassium salt is a toxic diterpenoid glycoside, which can be isolated from the fruit of Atractyloside. Atractyloside potassium salt is a highly effective and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibited the chloride channel in rat heart mitochondrial membrane. | ||
| M4886 | Selamectin | Parasite |
| Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM. | ||
| M5584 | Diphenidol hydrochloride | AChR/AChE |
| Difenidol hydrochloride; Diphenidol HCl | ||
| Diphenidol hydrochloride is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the study of vomiting and vertigo. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. | ||
| M5654 | Flunarizine 2HCl | Calcium Channel |
| KW-3149, R14950 | ||
| Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM. Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. | ||
| M5733 | Lercanidipine hydrochloride | Calcium Channel |
| Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. | ||
| M6431 | AM 92016 hydrochloride | Others |
| AM 92016 hydrochloride is a k V channel blocker. | ||
| M6499 | Bepridil hydrochloride | Calcium Channel |
| CERM 1978 | ||
| Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. | ||
| M6554 | CaCCinh-A01 | Chloride Channel |
| CaCCinh-A01 is a calcium-activated chloride channel (CaCC) inhibitor. | ||
| M6580 | Cesium chloride | Potassium Channel |
| Cesium chloride is a potassium channel blocker; neuroprotective. | ||
| M6625 | CP 339818 hydrochloride | Potassium Channel |
| CP 339818 hcl | ||
| CP 339818 hydrochloride is a non-peptide, potent KV1.3 channel blocker. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation. | ||
| M6741 | Gadolinium chloride | TRP Channel |
| Gadolinium chloride is a stretch-activated calcium channel blocker; calcium-sensing receptor agonist. | ||
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